Clinical Characteristics of Individuals Died with COVID-19 in Malaysia

M. Danial, Ann L Arulappen, S. A. Soelar, A. Ch’ng, I. Looi
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Abstract

Battling the COVID-19 pandemic still is the main agenda of many countries in the world today. This study aims to describe the clinical characteristics of COVID-19-related deaths in Malaysia in 2020. Data was obtained from the daily press conference on the COVID-19 situation in Malaysia. Only information on daily deaths were collected for the purpose of this study. A total of 471 COVID-19 deaths reported in Malaysia in 2020. Number of deaths reported for the age categories < 65 years old and ≥ 65 years old were almost equal. Majority of deaths were reported among male (66.2%), Malaysian (82.8%), from the state of Sabah (56.3%) and with comorbidities (75.4%). Commonly reported comorbidities were hypertension (53.1%), diabetes mellitus (37.6%) and heart disease (17.4%). Gout was more prevalent and attributed to significant rate of mortality in individuals ≥ 65 years old (6.1%; p = 0.011), whereas obesity (5.8%; p = 0.003) and asthma (4.5%; p = 0.040) were more prevalent and attributed to significant rate of mortality in individuals < 65 years old. Heart disease was more prevalent among males (n = 64, 20.5%; p = 0.013) and obesity was more prevalent among women (n = 11, 6.9%; p = 0.003). Furthermore, presence of comorbidities was significantly higher in Malaysians (p < 0.001) with two and more comorbidities (p = 0.007). Early detection of risk factors for critical conditions is urgently required to provide adequate supportive treatment.
马来西亚COVID-19死亡病例的临床特征
抗击新冠肺炎疫情仍然是当今世界许多国家的主要议程。本研究旨在描述2020年马来西亚covid -19相关死亡的临床特征。数据来自马来西亚新冠肺炎疫情每日新闻发布会。本研究仅收集了每日死亡人数的信息。2020年马来西亚共报告了471例COVID-19死亡病例。< 65岁和≥65岁年龄组报告的死亡人数几乎相等。大多数死亡报告为男性(66.2%)、马来西亚人(82.8%)、沙巴州人(56.3%)和合并症(75.4%)。常见的合并症有高血压(53.1%)、糖尿病(37.6%)和心脏病(17.4%)。痛风更为普遍,并归因于≥65岁人群的显著死亡率(6.1%;P = 0.011),而肥胖(5.8%;P = 0.003)和哮喘(4.5%;P = 0.040)更为普遍,并归因于65岁以下人群的显著死亡率。心脏病在男性中更为普遍(n = 64, 20.5%;P = 0.013),肥胖在女性中更为普遍(n = 11, 6.9%;P = 0.003)。此外,马来西亚人的合并症发生率明显更高(p < 0.001),有两种及以上合并症(p = 0.007)。迫切需要及早发现危重情况的危险因素,以提供适当的支持性治疗。
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