Application of the REAL-score prognostic index in decision making in rectal cancer surgery.

Daniel Aparicio-López, Isabel Gascón-Ferrer, Antonio Martínez-Germán, María P Santero-Ramírez, María N Sánchez-Fuentes, Carlos Gracia-Roche, Sef Saudí-Moro, María V Duque-Mallén
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Abstract

Background: Colorectal anastomosis leak (AL) is the most feared complication of rectal cancer surgery (1-19%) as it increases morbidity and mortality and worsens oncological outcomes in terms of local recurrence and survival. The publication of the REAL-score index makes it possible to predict the risk of AL and compare the expected results with those obtained.

Method: Observational, descriptive, longitudinal and retrospective study of patients operated on for rectal cancer at the Miguel Servet University Hospital, in Zaragoza, Spain, in 2019. Statistical analysis of morbidity and mortality outcome variables and the REAL-score index using ROC curves.

Results: Of 80 patients operated on for rectal cancer, colorectal anastomosis was performed in 52 and temporary ileostomy in 11 (21.2%). Morbidity was high (38.4%), but severe only in 7.7% (Clavien-Dindo IIIb), with no deaths. There were four dehiscences: one type B and three type C. A direct relationship between high risk of AL and the practice of temporary stoma is observed when the cut-off point of the REAL-score exceeds 14.74%.

Conclusions: REAL-score can help in decision-making in rectal cancer surgery. Above a cut-off point, the risk of AL would imply a selective ileostomy.

REAL-score预后指数在癌症直肠手术决策中的应用。
背景:结直肠吻合口漏(AL)是癌症手术最令人担忧的并发症(1-19%),因为它增加了发病率和死亡率,并恶化了局部复发和存活率方面的肿瘤结果。REAL评分指数的公布使得预测AL的风险并将预期结果与获得的结果进行比较成为可能。方法:对2019年西班牙萨拉戈萨Miguel Servet大学医院癌症直肠癌手术患者的观察、描述性、纵向和回顾性研究。使用ROC曲线对发病率和死亡率结果变量以及REAL评分指数进行统计分析。结果:80例癌症直肠癌患者中,52例行结直肠吻合,11例(21.2%)行临时回肠造瘘,发病率高(38.4%),但严重者仅为7.7%(Clavien-Dindo IIIb),无死亡。有四种裂开:一种是B型,三种是C型。当REAL-score的截止点超过14.74%时,观察到AL的高风险与临时造口的实践之间的直接关系。在临界点以上,AL的风险意味着选择性回肠造口术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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