Mixing Allograft and Xenograft for a Predictable Alveolar Ridge Preservation Procedure: A Case Series.

Samar Shaikh, Annie Li, Irina Dragan
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Abstract

Background: An alveolar ridge preservation (ARP) procedure is commonly performed to preserve ridge width and height for optimal dental implant placement. Mixing different sources of bone grafts may help maximize their properties to obtain predictable ARP results.

Objective: The aim of this case series is to highlight the clinical and radiographic outcomes of a combined allograft and xenograft approach for a predictable ARP procedure.

Materials and methods: Eleven clinical cases that required tooth extraction and future implant placement were selected for this case series. All surgeries were performed by a single clinician in a private practice setting. All cases underwent an ARP procedure, which included atraumatic extraction, degranulation, assessment of the socket, and the use of a combination of allograft and xenograft fibers/granules in a 1:1 mixing approach. Based on the socket defect, either a type I or type III collagen membrane was used during the procedure. In all cases CBCT imaging was done prior to surgical implant placement, and digital implant planning was performed integrating interdisciplinary best practices. Implant placement was carried out using manufacturer's recommendations.

Results: Five male and five female patients were included in the study, with one of the male patients having two teeth extracted for a total of 11 cases. The reasons for teeth extraction included fracture, endodontic failure, periodontal infection, and subgingival decay. Healing was uneventful after the ARP procedure for all patients. A minimum of 120 days elapsed between ARP and the surgical implant procedure. Complete radiographic bone fill was observed in the CBCT image for all extraction sites, and no additional bone augmentation was needed at the time of implant placement.

Conclusion: This case series demonstrates that based on clinical and radiographic outcomes, a combination of allogenic and xenogenic bone substitute can be utilized to obtain predictable results following ARP. Future randomized controlled trials that can compare different ratios between the two biomaterials are indicated to guide clinicians in the mixing protocols and their outcomes.

同种异体移植物和异种移植物混合用于可预测的牙槽嵴保存程序:一个病例系列。
背景:牙槽嵴保留术(ARP)通常用于保留牙槽嵴的宽度和高度,以获得最佳的种植体位置。混合不同来源的骨移植物可能有助于最大限度地提高其特性,以获得可预测的ARP结果。目的:本病例系列的目的是强调同种异体移植物和异种移植物联合方法的临床和放射学结果,以进行可预测的ARP手术。材料和方法:本病例系列选择了11例需要拔牙和未来植入的临床病例。所有手术都由一名临床医生在私人诊所进行。所有病例都接受了ARP手术,包括无创伤提取、脱颗粒、评估牙槽窝,以及以1:1混合的方式使用同种异体移植物和异种移植物纤维/颗粒的组合。基于牙槽缺损,在手术过程中使用I型或III型胶原膜。在所有病例中,CBCT成像都是在手术植入物放置之前进行的,数字植入物规划是结合跨学科最佳实践进行的。按照制造商的建议进行植入。结果:研究包括5名男性和5名女性患者,其中1名男性患者共11例拔除了两颗牙齿。拔牙的原因包括骨折、牙髓病、牙周感染和龈下蛀牙。ARP手术后,所有患者的康复都很顺利。ARP和手术植入程序之间至少经过了120天。在所有提取部位的CBCT图像中观察到完全的放射学骨填充,并且在植入时不需要额外的骨增强。结论:该病例系列表明,根据临床和放射学结果,同种异体和异种骨替代物的组合可以在ARP后获得可预测的结果。未来的随机对照试验可以比较两种生物材料之间的不同比例,这有助于指导临床医生制定混合方案及其结果。
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