Maternal Vertical Microbial Transmission During Skin-to-Skin Care.

IF 1.6 4区医学 Q2 NURSING

Advances in Neonatal Care Pub Date : 2023-12-01 Epub Date: 2023-10-18 DOI:10.1097/ANC.0000000000001109

Maryam Hamidi, Angelica Cruz-Lebrón, Naseer Sangwan, Mary Ann Blatz, Alan D Levine

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引用次数: 0

Abstract

Background: Skin-to-skin (STS) care may contribute to mother-to-infant vertical microbial transmission by enriching the preterm infant's microbiome.

Purpose: The purpose of this observational study was to define the impact of increased STS care duration on vertical microbial transmission and consequently modulate oral and intestinal microbial balance.

Methods: Postpartum women and their preterm infants, 31 to 34 weeks' gestation (n = 25), were recruited for this study. Using 16S rRNA sequencing, we compared α- and β-diversity with the Shannon and Chao indexes and nonmetric multidimensional scaling, respectively, and relative abundance of microbial communities, which refers to the percentage of specific organisms in a community, from mother's chest skin, preterm infant's oral cavity, and preterm infant's stool samples. Effects of STS care on vertical transmission were determined by comparing oral and stool microbial population of preterm infants who received low exposure (<40 minutes) with that of preterm infants who received high exposure (>60 minutes).

Results: Microbial composition, diversity, and relative abundance were different across the 3 sites. Oral microbial richness was less and stool richness was greater among the preterm infants in the high STS care group. Oral and intestinal microbial diversity and composition were different between the groups, with the relative abundance of Gemella and Aggregatibacter genera and Lachnospiraceae family significantly greater in the stool of the high STS care group.

Implications for practice: Results suggest that STS care may be an effective method to enhance microbial communities among preterm infants.

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母亲在皮肤到皮肤护理过程中的垂直微生物传播。

背景：皮肤对皮肤（STS）护理可能通过丰富早产儿的微生物组来促进母婴垂直微生物传播。目的：本观察性研究的目的是确定STS护理时间增加对垂直微生物传播的影响，从而调节口腔和肠道微生物平衡。方法：本研究招募了妊娠31至34周的产后妇女及其早产儿（n=25）。使用16S rRNA测序，我们将α-和β-多样性分别与Shannon和Chao指数和非度量多维标度以及微生物群落的相对丰度进行了比较，微生物群落是指群落中特定生物的百分比，包括母亲的胸部皮肤、早产儿的口腔和早产儿的粪便样本。STS护理对垂直传播的影响是通过比较接受低暴露（60分钟）的早产儿的口腔和粪便微生物群来确定的。结果：3个地点的微生物组成、多样性和相对丰度不同。在高STS护理组的早产儿中，口腔微生物丰富度较低，粪便丰富度较高。两组之间的口腔和肠道微生物多样性和组成不同，高STS护理组的粪便中Gemella属和Aggregatibacter属以及Lachnospiraceae科的相对丰度明显更高。实践意义：研究结果表明，STS护理可能是增强早产儿微生物群落的有效方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Neonatal Care NURSING-

CiteScore

2.60

自引率

5.90%

发文量

101

期刊介绍： Advances in Neonatal Care takes a unique and dynamic approach to the original research and clinical practice articles it publishes. Addressing the practice challenges faced every day—caring for the 40,000-plus low-birth-weight infants in Level II and Level III NICUs each year—the journal promotes evidence-based care and improved outcomes for the tiniest patients and their families. Peer-reviewed editorial includes unique and detailed visual and teaching aids, such as Family Teaching Toolbox, Research to Practice, Cultivating Clinical Expertise, and Online Features. Each issue offers Continuing Education (CE) articles in both print and online formats.