Effectiveness of CT-guided percutaneous cordotomy in intractable cancer pain: Experience in 14 patients.

IF 2.5 3区医学 Q2 ANESTHESIOLOGY

Pain Practice Pub Date : 2024-02-01 Epub Date: 2023-10-17 DOI:10.1111/papr.13307

Mert Akbaş, Gözde Dağıstan

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Abstract

Background: Severe and treatment-resistant pain is a major issue for patients with cancer. Cordotomy is an effective approach for addressing severe cancer-related pain. It is based on blocking the transmission of pain by damaging the lateral spinothalamic tract.

Methods: Computed tomography guided cordotomy was performed on 14 patients who did not respond to medical and interventional pain management methods.

Results: Fourteen patients with cancer pain underwent CT-guided percutaneous cordotomy. Pain relief was reported in 86% of the patients. The visual analog scale values before and after cordotomy were compared and a significant difference was found (p = 0.0001). The improvement in the Karnofsky Performance Scale score of the patients was found to be statistically significant (p = 0.0001).

Conclusion: We believe that CT-guided cordotomy, performed by experienced hands in a team of experienced individuals and applied to the right patients, is an effective treatment. However, it is crucial to exercise extreme caution regarding potential side effects and serious complications during the cordotomy procedure.

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CT引导下经皮脊髓切开术治疗顽固性癌症疼痛的疗效：14例患者的经验。

背景：对癌症患者来说，剧烈疼痛和耐治性疼痛是一个主要问题。脐带切开术是治疗严重癌症相关疼痛的有效方法。它的基础是通过损伤脊髓丘脑外侧束来阻断疼痛的传播。方法：对14例对药物和介入性疼痛管理方法没有反应的患者进行计算机断层扫描引导下的脊髓切开术。结果：14例癌症疼痛患者行CT引导下经皮脊髓切开术。据报道，86%的患者疼痛减轻。比较声带切开术前后的视觉模拟量表值，发现差异有统计学意义（p = 0.0001）。发现患者的Karnofsky性能量表评分的改善具有统计学意义（p = 0.0001）。结论：我们相信，由经验丰富的人组成的团队中经验丰富的手进行CT引导下的脊髓切开术，并应用于合适的患者，是一种有效的治疗方法。然而，至关重要的是，在脐带切开术过程中，要格外小心潜在的副作用和严重并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pain Practice ANESTHESIOLOGY-CLINICAL NEUROLOGY

CiteScore

5.60

自引率

3.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Pain Practice, the official journal of the World Institute of Pain, publishes international multidisciplinary articles on pain and analgesia that provide its readership with up-to-date research, evaluation methods, and techniques for pain management. Special sections including the Consultant’s Corner, Images in Pain Practice, Case Studies from Mayo, Tutorials, and the Evidence-Based Medicine combine to give pain researchers, pain clinicians and pain fellows in training a systematic approach to continuing education in pain medicine. Prior to publication, all articles and reviews undergo peer review by at least two experts in the field.

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