Treatment Rates for Mental Disorders Among Children and Adolescents: A Systematic Review and Meta-Analysis.

IF 9.7 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Sifan Wang, Qiongxian Li, Jin Lu, Hailiang Ran, Yusan Che, Die Fang, Xuemeng Liang, Hao Sun, Lin Chen, Junwei Peng, Yuanyu Shi, Yuanyuan Xiao
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引用次数: 0

Abstract

Importance: Mental disorders among children and adolescents are global health concerns. Published studies have provided discordant results regarding treatment rates for mental disorders among youths.

Objective: To estimate combined treatment rates for several common psychiatric disorders among children and adolescents.

Data sources: PubMed, Web of Science, PsycINFO, Scopus, and Embase were searched from database inception until September 23, 2022, and supplemented with hand-searching of reference lists.

Study selection: Included studies were those that used validated methods to report treatment rates for any mental disorder, depressive disorders, anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), and behavior disorders among children and adolescents.

Data extraction and synthesis: This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guideline. Two reviewers independently assessed study eligibility, extracted data, and scored quality. Studies with a Joanna Briggs Institute score of 5 or more were included in the meta-analysis. Treatment rates were pooled using random-effects models. Subgroup analyses were performed to investigate the association with treatment rates of factors, such as year of data collection, World Health Organization region, age, income level, timeframe of diagnosis, informant source, service type, sample origin, and internalizing or externalizing disorder.

Main outcomes and measures: Treatment rates for mental disorders among children and adolescents were the main outcomes, measured as percentage estimates.

Results: Forty studies were included in the analysis, comprising 310 584 children and adolescents, with boys accounting for 39% of participants (sex was not reported in 10 studies). The pooled treatment rate was 38% (95% CI, 30%-45%) for any mental disorder, 36% (95% CI, 29%-43%) for depressive disorders, 31% (95% CI, 21%-42%) for anxiety disorders, 58% (95% CI, 42%-73%) for ADHD, and 49% (95% CI, 35%-64%) for behavior disorders. Age, income level, and region were significantly associated with the combined treatment rates of mental disorders in children and adolescents. The treatment rate for depressive disorders was higher among adolescents than children (36% [95% CI, 25%-46%] vs 11% [95% CI, 0%-25%]), whereas the treatment rate for anxiety disorders was higher among children than adolescents (64% [95% CI, 52%-75%] vs 20% [95% CI, 9%-30%]). The treatment rate for any mental disorder in lower-middle income countries was 6% (95% CI, 2%-14%), in upper-middle income countries was 24% (95% CI, 2%-47%), and in high-income countries was 43% (95% CI, 35%-52%). For depressive disorders, treatment rates were higher in the Americas (40% [95% CI, 30%-51%]) than in Europe (28% [95% CI, 13%-43%]) and the Western Pacific region (6% [95% CI, 1%-16%]).

Conclusions and relevance: This study suggests that, in general, the treatment rates for mental disorders among children and adolescents were low, especially for depression and anxiety. Targeted intervention policies and effective measures should be designed and implemented to improve treatment rates of psychiatric disorders among youths.

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儿童和青少年精神障碍的治疗率:系统综述和荟萃分析。
重要性:儿童和青少年的精神障碍是全球关注的健康问题。已发表的研究在青少年精神障碍的治疗率方面提供了不一致的结果。目的:评估儿童和青少年几种常见精神疾病的综合治疗率。数据来源:PubMed、Web of Science、PsycINFO、Scopus和Embase从数据库创建到2022年9月23日进行了搜索,并辅以参考文献列表的手动搜索。研究选择:纳入的研究是那些使用有效方法报告儿童和青少年中任何精神障碍、抑郁障碍、焦虑障碍、注意力缺陷/多动障碍(ADHD)和行为障碍的治疗率的研究。数据提取和综合:本研究遵循系统评价和荟萃分析(PRISMA)报告指南的首选报告项目。两名评审员独立评估研究合格性、提取数据并对质量进行评分。乔安娜·布里格斯研究所得分为5分或以上的研究被纳入荟萃分析。使用随机效应模型汇总治疗率。进行亚组分析,以调查数据收集年份、世界卫生组织地区、年龄、收入水平、诊断时间、信息来源、服务类型、样本来源以及内化或外化障碍等因素与治疗率的关系。主要结果和衡量标准:儿童和青少年的精神障碍治疗率是主要结果,以百分比估计值衡量。结果:分析包括40项研究,包括310项 584名儿童和青少年,其中男孩占参与者的39%(10项研究中未报告性别)。任何精神障碍的合并治疗率为38%(95%CI,30%-45%),抑郁症为36%(95%CI,29%-43%),焦虑症为31%(95%CI、21%-42%),多动症为58%(95%CI、42%-73%),行为障碍为49%(95%CI、35%-64%)。年龄、收入水平和地区与儿童和青少年精神障碍的综合治疗率显著相关。青少年的抑郁症治疗率高于儿童(36%[95%CI,25%-46%]vs 11%[95%CI,0%-25%]),而儿童的焦虑症治疗率高于青少年(64%[95%可信区间,52%-75%]vs 20%[95%CI,9%-30%])。中低收入国家的任何精神障碍的治疗率为6%(95%置信区间,2%-14%),中上收入国家为24%(95%置信度,2%-47%),高收入国家为43%(95%可信区间,35%-52%)。对于抑郁症,美洲的治疗率(40%[95%CI,30%-51%])高于欧洲(28%[95%CI,13%-43%])和西太平洋地区(6%[95%可信区间,1%-16%])。结论和相关性:本研究表明,总体而言,儿童和青少年的精神障碍治疗率较低,尤其是抑郁症和焦虑症。应制定和实施有针对性的干预政策和有效措施,以提高青少年精神障碍的治疗率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
JAMA Network Open
JAMA Network Open Medicine-General Medicine
CiteScore
16.00
自引率
2.90%
发文量
2126
审稿时长
16 weeks
期刊介绍: JAMA Network Open, a member of the esteemed JAMA Network, stands as an international, peer-reviewed, open-access general medical journal.The publication is dedicated to disseminating research across various health disciplines and countries, encompassing clinical care, innovation in health care, health policy, and global health. JAMA Network Open caters to clinicians, investigators, and policymakers, providing a platform for valuable insights and advancements in the medical field. As part of the JAMA Network, a consortium of peer-reviewed general medical and specialty publications, JAMA Network Open contributes to the collective knowledge and understanding within the medical community.
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