Efficacy of epidural infiltration in the management of pain and disability due to acute and subacute lumbosacral radiculopathy

Jose Manuel Rabanal Llevot , Amaia Muñoz Alonso , Alberto Taborga Echevarría , Jose Angel Martínez Agueros , Sergio Maldonado Vega
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Abstract

Background and Objective

Epidural infiltrations are used for treatment of low back pain and sciatica. Linked to lumbar radiculopathy (lumbosacral radicular syndrome). This study evaluates the efficacy of epidural infiltration by different routes to reduce pain intensity, disability and return to work.

Methods

Is a prospective observational study in one hundred consecutive patients sent to pain unit for severe lumbo-sacral radiculopaty. We analyze the efficacy on pain relief (Visual Analogue Scale) and funcional status at two weeks, one month, and three months after epidural injection of local anesthetics and esteroids with differents approachs (interlaminar, caudal and transforaminal).

Results

Ninety nine patients (46.5% men, 53.5 women) were finally enrrolled in the study. Mean age was 57.47 ± 11.1 years. The caudal approach was used in 58.6% patients, 23.2% transforaminal approach, and 18.2% interlaminar approach. A significant pain relief was found in all times studied (EAV 7.48 ± 1.5 basal; 6.2 ± 0,9 at 15 days; 6.3 ± 1.2 at one month; 6.15 ± 1.3 at 3 months, p < 0.05). Transforaminal approach was superior to caudal or interlaminal. Seventy percent in time off work patients returned to work after epidural inyections.

Conclusions

Epidural local anesthetics with esteroids injections for lumbo-sacral radiculopathy were effective for low back pain, improved functional status and promoted return to work. Transforaminal approach is superior to others.

硬膜外浸润治疗急性和亚急性腰骶神经根病引起的疼痛和残疾的疗效。
背景和目的:硬膜外浸润用于治疗腰痛和坐骨神经痛。与腰神经根病(腰骶神经根综合征)有关。本研究评估了不同途径硬膜外浸润对减轻疼痛强度、致残和重返工作岗位的疗效。方法:这是一项前瞻性观察性研究,对连续100名因严重腰骶神经根痛而被送往疼痛病房的患者进行研究。我们分析了硬膜外注射局麻药和酯类药物后两周、一个月和三个月的镇痛效果(视觉模拟量表)和功能状态。平均年龄为57.47岁 ± 11.1年。58.6%的患者采用尾侧入路,23.2%采用经孔入路,18.2%采用层间入路。在所研究的所有时间内都发现了显著的疼痛缓解(EAV 7.48 ± 1.5基底;6.2 ± 第15天为0.9;6.3 ± 1.2一个月;6.15 ± 1.3在3 月,p 结论:硬膜外局麻药联合注射酯类药物治疗腰骶神经根病可有效治疗腰痛,改善功能状态,促进重返工作岗位。经口入路优于其他入路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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