NF-κB and Related Autoimmune and Autoinflammatory Diseases

IF 2.6 4区医学 Q2 RHEUMATOLOGY

Rheumatic Disease Clinics of North America Pub Date : 2023-08-01 DOI:10.1016/j.rdc.2023.06.008

George E. Freigeh MD, MA , Thomas F. Michniacki MD

引用次数: 0

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κB和相关的自身免疫和自身炎症性疾病。

NF-岛B通路是一种重要的信号通路，与多种临床疾病的发展有关。许多细胞过程汇聚在这一途径上，从而导致细胞增殖和存活。该途径及其上游调节因子的缺陷已被描述为导致免疫缺陷。然而，越来越多的文献将自身免疫性和自身炎症性疾病与NF-κB通路功能障碍联系起来。这篇综述是对这些疾病文献的最新评价。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rheumatic Disease Clinics of North America 医学-风湿病学

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Rheumatic Disease Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue (February, May, August, and November) focuses on a single topic in rheumatology and is presented under the direction of an experienced editor. Topics include osteoarthritis, rheumatoid arthritis, crystal diseases, MSK exam, disorders of the bone, immunodeficiency states, lupus, neuromuscular disease, pain disorders, scleroderma, vasculitis, pediatrics, therapeutics, treatment guidelines, and treatment modalities.