Cost-Effectiveness of Cardiac Rehabilitation in Older Adults With Coronary Heart Disease.

IF 3.3 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Donald S Shepard, Shehreen Zakir, Diann E Gaalema, Philip A Ades
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Abstract

Purpose: While cardiac rehabilitation (CR) is recommended and effective following acute cardiac events, it remains underutilized, particularly in older adults. A study of 601 099 Medicare beneficiaries ≥65 yr hospitalized for coronary heart disease compared 5-yr mortality in users and nonusers of CR. Using instrumental variables (IV), CR improved mortality by 8.0% ( P < .001). A validation analysis based on 70 040 propensity-based (PB) matched pairs gave a similar gain (8.3%, P < .0001). The present cost-effectiveness analysis builds on these mortality results.

Methods: Using the framework of the Second Panel on Cost-Effectiveness Analysis, we calculated the incremental cost-effectiveness ratio (ICER) gained due to CR. We accessed the costs from this cohort, inflated to 2022 prices, and assessed the relationship of quality-adjusted life years (QALY) to life years from a systematic review. We estimated the ICER of CR by modeling lifetime costs and QALY from national life tables using IV and PB.

Results: Using IV, CR added 1.344 QALY (95% CI, 0.543-2.144) and $40 472 in costs over the remaining lifetimes of participants. The ICER was $30 188 (95% CI, $18 175-$74 484)/QALY over their lifetimes. Using the PB analysis, the corresponding lifetime values were 2.018 (95% CI, 1.001-3.035) QALY, $66 590, and an ICER of $32 996 (95% CI, $21 942-$66 494)/QALY.

Conclusions: Cardiac rehabilitation was highly cost-effective using guidelines established by the World Health Organization and the US Department of Health and Human Services. The favorable clinical effectiveness and cost-effectiveness of CR, along with low use by Medicare beneficiaries, support the need to increase CR use.

老年冠心病患者心脏康复的成本效益。
目的:虽然心脏康复(CR)在急性心脏事件后是推荐的且有效的,但它仍然没有得到充分利用,尤其是在老年人中。一项针对601 099名65岁以上因冠心病住院的联邦医疗保险受益人的研究比较了CR使用者和非使用者的5年死亡率。使用工具变量(IV),CR将死亡率提高了8.0%(P<.001)。基于70 040对基于倾向(PB)的配对进行的验证分析得出了类似的结果(8.3%,P<.0001)。目前的成本效益分析建立在这些死亡率结果的基础上。方法:使用第二个成本效益分析小组的框架,我们计算了因CR而获得的增量成本效益比(ICER)。我们获取了该队列的成本,并将其膨胀到2022年的价格,并从系统回顾中评估了质量调整生命年(QALY)与生命年的关系。我们通过使用IV和PB从国家寿命表中建模寿命成本和QALY来估计CR的ICER。结果:使用IV,CR在参与者的剩余寿命内增加了1.344 QALY(95%CI,0.543-2.144)和40 472美元的成本。在他们的一生中,ICER为30188美元(95%置信区间,18175美元-7484美元)/QLY。使用PB分析,相应的寿命值为2.018(95%CI,1.001-3.035)QALY,66 590美元,ICER为32 996美元(95%CI,21 942美元-66 494美元)/QALY。结论:根据世界卫生组织和美国卫生与公众服务部制定的指南,心脏康复具有很高的成本效益。CR良好的临床有效性和成本效益,以及医疗保险受益人的低使用率,支持了增加CR使用的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.40
自引率
34.20%
发文量
164
审稿时长
6-12 weeks
期刊介绍: JCRP was the first, and remains the only, professional journal dedicated to improving multidisciplinary clinical practice and expanding research evidence specific to both cardiovascular and pulmonary rehabilitation. This includes exercise testing and prescription, behavioral medicine, and cardiopulmonary risk factor management. In 2007, JCRP expanded its scope to include primary prevention of cardiovascular and pulmonary diseases. JCRP publishes scientific and clinical peer-reviewed Original Investigations, Reviews, and Brief or Case Reports focused on the causes, prevention, and treatment of individuals with cardiovascular or pulmonary diseases in both a print and online-only format. Editorial features include Editorials, Invited Commentaries, Literature Updates, and Clinically-relevant Topical Updates. JCRP is the official Journal of the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac Rehabilitation.
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