Cost-Effectiveness of Cardiac Rehabilitation in Older Adults With Coronary Heart Disease.

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
ACS Applied Electronic Materials Pub Date : 2024-03-01 Epub Date: 2023-10-04 DOI:10.1097/HCR.0000000000000827
Donald S Shepard, Shehreen Zakir, Diann E Gaalema, Philip A Ades
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Abstract

Purpose: While cardiac rehabilitation (CR) is recommended and effective following acute cardiac events, it remains underutilized, particularly in older adults. A study of 601 099 Medicare beneficiaries ≥65 yr hospitalized for coronary heart disease compared 5-yr mortality in users and nonusers of CR. Using instrumental variables (IV), CR improved mortality by 8.0% ( P < .001). A validation analysis based on 70 040 propensity-based (PB) matched pairs gave a similar gain (8.3%, P < .0001). The present cost-effectiveness analysis builds on these mortality results.

Methods: Using the framework of the Second Panel on Cost-Effectiveness Analysis, we calculated the incremental cost-effectiveness ratio (ICER) gained due to CR. We accessed the costs from this cohort, inflated to 2022 prices, and assessed the relationship of quality-adjusted life years (QALY) to life years from a systematic review. We estimated the ICER of CR by modeling lifetime costs and QALY from national life tables using IV and PB.

Results: Using IV, CR added 1.344 QALY (95% CI, 0.543-2.144) and $40 472 in costs over the remaining lifetimes of participants. The ICER was $30 188 (95% CI, $18 175-$74 484)/QALY over their lifetimes. Using the PB analysis, the corresponding lifetime values were 2.018 (95% CI, 1.001-3.035) QALY, $66 590, and an ICER of $32 996 (95% CI, $21 942-$66 494)/QALY.

Conclusions: Cardiac rehabilitation was highly cost-effective using guidelines established by the World Health Organization and the US Department of Health and Human Services. The favorable clinical effectiveness and cost-effectiveness of CR, along with low use by Medicare beneficiaries, support the need to increase CR use.

老年冠心病患者心脏康复的成本效益。
目的:虽然心脏康复(CR)在急性心脏事件后是推荐的且有效的,但它仍然没有得到充分利用,尤其是在老年人中。一项针对601 099名65岁以上因冠心病住院的联邦医疗保险受益人的研究比较了CR使用者和非使用者的5年死亡率。使用工具变量(IV),CR将死亡率提高了8.0%(P<.001)。基于70 040对基于倾向(PB)的配对进行的验证分析得出了类似的结果(8.3%,P<.0001)。目前的成本效益分析建立在这些死亡率结果的基础上。方法:使用第二个成本效益分析小组的框架,我们计算了因CR而获得的增量成本效益比(ICER)。我们获取了该队列的成本,并将其膨胀到2022年的价格,并从系统回顾中评估了质量调整生命年(QALY)与生命年的关系。我们通过使用IV和PB从国家寿命表中建模寿命成本和QALY来估计CR的ICER。结果:使用IV,CR在参与者的剩余寿命内增加了1.344 QALY(95%CI,0.543-2.144)和40 472美元的成本。在他们的一生中,ICER为30188美元(95%置信区间,18175美元-7484美元)/QLY。使用PB分析,相应的寿命值为2.018(95%CI,1.001-3.035)QALY,66 590美元,ICER为32 996美元(95%CI,21 942美元-66 494美元)/QALY。结论:根据世界卫生组织和美国卫生与公众服务部制定的指南,心脏康复具有很高的成本效益。CR良好的临床有效性和成本效益,以及医疗保险受益人的低使用率,支持了增加CR使用的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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