Regulation of Cell Behavior by Hydrostatic Pressure.

IF 12.2 1区工程技术 Q1 MECHANICS

Applied Mechanics Reviews Pub Date : 2019-07-01 Epub Date: 2019-07-23 DOI:10.1115/1.4043947

Shaobao Liu, Ru Tao, Ming Wang, Jin Tian, Guy M Genin, Tian Jian Lu, Feng Xu

引用次数: 0

Abstract

Hydrostatic pressure (HP) regulates diverse cell behaviors including differentiation, migration, apoptosis, and proliferation. Abnormal HP is associated with pathologies including glaucoma and hypertensive fibrotic remodeling. In this review, recent advances in quantifying and predicting how cells respond to HP across several tissue systems are presented, including tissues of the brain, eye, vasculature and bladder, as well as articular cartilage. Finally, some promising directions on the study of cell behaviors regulated by HP are proposed.

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静水压力对细胞行为的调节。

静水压（HP）调节多种细胞行为，包括分化、迁移、凋亡和增殖。HP异常与青光眼和高血压纤维变性重塑等病理有关。在这篇综述中，介绍了在量化和预测几个组织系统中细胞对HP的反应方面的最新进展，包括大脑、眼睛、脉管系统和膀胱的组织，以及关节软骨。最后，对HP调控细胞行为的研究提出了一些有前景的方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Mechanics Reviews 物理-力学

CiteScore

28.20

自引率

0.70%

发文量

审稿时长

>12 weeks

期刊介绍： Applied Mechanics Reviews (AMR) is an international review journal that serves as a premier venue for dissemination of material across all subdisciplines of applied mechanics and engineering science, including fluid and solid mechanics, heat transfer, dynamics and vibration, and applications.AMR provides an archival repository for state-of-the-art and retrospective survey articles and reviews of research areas and curricular developments. The journal invites commentary on research and education policy in different countries. The journal also invites original tutorial and educational material in applied mechanics targeting non-specialist audiences, including undergraduate and K-12 students.