Gait ataxia in alcohol use disorder: A systematic review.

IF 3.2 2区心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY

Psychology of Addictive Behaviors Pub Date : 2024-06-01 Epub Date: 2023-09-28 DOI:10.1037/adb0000958

Nicolaj Mistarz, Lind Canfield, Dorthe Grüner Nielsen, Lotte Skøt, Angelina Isabella Mellentin

{"title":"Gait ataxia in alcohol use disorder: A systematic review.","authors":"Nicolaj Mistarz, Lind Canfield, Dorthe Grüner Nielsen, Lotte Skøt, Angelina Isabella Mellentin","doi":"10.1037/adb0000958","DOIUrl":null,"url":null,"abstract":"Objective: A severe and long-term alcohol use can have adverse effects on lower limb function. Over time, some individuals may develop gait ataxia, which refers to the impairment of controlled lower body movements that are important for walking and maintaining proper gait. Gait ataxia is well-documented in patients who have been diagnosed with alcohol-related Wernicke-Korsakoff syndrome (WKS); however, less is known on how common ataxia is among patients with alcohol use disorder (AUD) without WKS. To date, no study has systematically reviewed the evidence focusing on patients suffering only from AUD. Our aim was to perform a qualitative synthesis of the existing literature examining behavioral signs of gait ataxia among abstinent patients with AUD.Method: Two facets were created encompassing keywords for \"alcohol use disorder\" and \"measures of gait ataxia.\" Databases, including EMBASE, APA PsycInfo, Medline, and Cochrane Library, were searched for studies, and a quality assessment was performed.Results: Ten studies were identified (37 ≥ ns ≤ 247), which were all rated as being of moderate (N = 7) to good quality (N = 3). The age range was 31.4-53.4 years (weighted mean age: 53.6 years), and 78.3% of the participants were male. Eight studies found that patients with AUD and without WKS exhibited behavioral signs of gait ataxia.Conclusions: Although there is evidence of gait ataxia among patients with AUD, heterogeneous results and methodological shortcomings such as lack of screening for neurocognitive deficits deem these findings preliminary and highlight the need for more research in the future. (PsycInfo Database Record (c) 2024 APA, all rights reserved).","PeriodicalId":48325,"journal":{"name":"Psychology of Addictive Behaviors","volume":" ","pages":"507-517"},"PeriodicalIF":3.2000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychology of Addictive Behaviors","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1037/adb0000958","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/28 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: A severe and long-term alcohol use can have adverse effects on lower limb function. Over time, some individuals may develop gait ataxia, which refers to the impairment of controlled lower body movements that are important for walking and maintaining proper gait. Gait ataxia is well-documented in patients who have been diagnosed with alcohol-related Wernicke-Korsakoff syndrome (WKS); however, less is known on how common ataxia is among patients with alcohol use disorder (AUD) without WKS. To date, no study has systematically reviewed the evidence focusing on patients suffering only from AUD. Our aim was to perform a qualitative synthesis of the existing literature examining behavioral signs of gait ataxia among abstinent patients with AUD.

Method: Two facets were created encompassing keywords for "alcohol use disorder" and "measures of gait ataxia." Databases, including EMBASE, APA PsycInfo, Medline, and Cochrane Library, were searched for studies, and a quality assessment was performed.

Results: Ten studies were identified (37 ≥ ns ≤ 247), which were all rated as being of moderate (N = 7) to good quality (N = 3). The age range was 31.4-53.4 years (weighted mean age: 53.6 years), and 78.3% of the participants were male. Eight studies found that patients with AUD and without WKS exhibited behavioral signs of gait ataxia.

Conclusions: Although there is evidence of gait ataxia among patients with AUD, heterogeneous results and methodological shortcomings such as lack of screening for neurocognitive deficits deem these findings preliminary and highlight the need for more research in the future. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

查看原文本刊更多论文

酒精使用障碍中的步态共济失调：一项系统综述。

目的：长期严重饮酒会对下肢功能产生不良影响。随着时间的推移，一些人可能会出现步态共济失调，这是指对行走和保持正确步态很重要的受控下半身运动受损。Gait共济失调在被诊断为酒精相关的Wernicke-Korsakoff综合征（WKS）的患者中有充分的记录；然而，关于共济失调在没有WKS的酒精使用障碍（AUD）患者中的常见程度，人们知之甚少。到目前为止，还没有任何研究系统地回顾仅关注AUD患者的证据。我们的目的是对现有文献进行定性综合，研究AUD禁欲患者步态共济失调的行为体征。方法：创建两个方面，包括“酒精使用障碍”和“步态共济失调测量”的关键词。检索数据库，包括EMBASE、APA PsycInfo、Medline和Cochrane Library，并进行质量评估。结果：确定了10项研究（37项≥ns≤247项），这些研究都被评为中等（N=7）至良好质量（N=3）。年龄范围为31.4-53.4岁（加权平均年龄：53.6岁），78.3%的参与者为男性。八项研究发现，患有AUD和不患有WKS的患者表现出步态共济失调的行为体征。结论：尽管有证据表明AUD患者存在步态共济失调，但异质性结果和方法学缺陷（如缺乏神经认知缺陷筛查）认为这些发现是初步的，并强调了未来需要更多研究。（PsycInfo数据库记录（c）2023 APA，保留所有权利）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Psychology of Addictive Behaviors Multiple-

CiteScore

4.90

自引率

11.80%

发文量

165

期刊介绍： Psychology of Addictive Behaviors publishes peer-reviewed original articles related to the psychological aspects of addictive behaviors. The journal includes articles on the following topics: - alcohol and alcoholism - drug use and abuse - eating disorders - smoking and nicotine addiction, and other excessive behaviors (e.g., gambling) Full-length research reports, literature reviews, brief reports, and comments are published.