Improved tomographic reconstruction of large-scale real-world data by filter optimization

IF 3.56 Q1 Medicine
Daniël M. Pelt, Vincent De Andrade
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引用次数: 11

Abstract

In advanced tomographic experiments, large detector sizes and large numbers of acquired datasets can make it difficult to process the data in a reasonable time. At the same time, the acquired projections are often limited in some way, for example having a low number of projections or a low signal-to-noise ratio. Direct analytical reconstruction methods are able to produce reconstructions in very little time, even for large-scale data, but the quality of these reconstructions can be insufficient for further analysis in cases with limited data. Iterative reconstruction methods typically produce more accurate reconstructions, but take significantly more time to compute, which limits their usefulness in practice. In this paper, we present the application of the SIRT-FBP method to large-scale real-world tomographic data. The SIRT-FBP method is able to accurately approximate the simultaneous iterative reconstruction technique (SIRT) method by the computationally efficient filtered backprojection (FBP) method, using precomputed experiment-specific filters. We specifically focus on the many implementation details that are important for application on large-scale real-world data, and give solutions to common problems that occur with experimental data. We show that SIRT-FBP filters can be computed in reasonable time, even for large problem sizes, and that precomputed filters can be reused for future experiments. Reconstruction results are given for three different experiments, and are compared with results of popular existing methods. The results show that the SIRT-FBP method is able to accurately approximate iterative reconstructions of experimental data. Furthermore, they show that, in practice, the SIRT-FBP method can produce more accurate reconstructions than standard direct analytical reconstructions with popular filters, without increasing the required computation time.

Abstract Image

基于滤波器优化的大规模真实数据层析重建
在高级层析实验中,由于探测器尺寸大,采集的数据集数量多,很难在合理的时间内处理数据。同时,所获得的投影往往在某种程度上受到限制,例如投影数量少或信噪比低。直接分析重建方法能够在很短的时间内产生重建,即使是大规模的数据,但是在数据有限的情况下,这些重建的质量可能不足以进一步分析。迭代重建方法通常产生更精确的重建,但需要花费更多的时间来计算,这限制了它们在实践中的实用性。在本文中,我们提出了SIRT-FBP方法在大规模真实世界层析数据中的应用。SIRT-FBP方法使用预先计算的实验特定滤波器,通过计算效率高的滤波反向投影(FBP)方法,能够准确地近似于同步迭代重建技术(SIRT)方法。我们特别关注许多对大规模现实数据应用很重要的实现细节,并给出了实验数据中出现的常见问题的解决方案。我们证明SIRT-FBP滤波器可以在合理的时间内计算,即使对于大的问题规模,并且预先计算的滤波器可以在未来的实验中重复使用。给出了三种不同实验的重建结果,并对现有常用方法的重建结果进行了比较。结果表明,SIRT-FBP方法能够准确逼近实验数据的迭代重建。此外,他们表明,在实践中,SIRT-FBP方法可以产生比使用流行滤波器的标准直接解析重建更精确的重建,而不会增加所需的计算时间。
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来源期刊
Advanced Structural and Chemical Imaging
Advanced Structural and Chemical Imaging Medicine-Radiology, Nuclear Medicine and Imaging
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