Practical Guidance on [177Lu]Lu-PSMA-617 Treatment, Including Radiation Safety, Adverse Event Monitoring, and Patient Counseling.

IF 1.3 4区医学 Q3 NURSING

Clinical journal of oncology nursing Pub Date : 2023-09-15 DOI:10.1188/23.CJON.539-547

Avery Spitz, Rebecca Floyd, Jennifer Sutton, Linda Gardner

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引用次数: 0

Abstract

Background: The approval of the prostate-specific membrane antigen (PSMA)-targeted radio-ligand therapy [177Lu]Lu-PSMA-617 represents a shift toward precision medicine-based treatments for metastatic castration-resistant prostate cancer.

Objectives: This review aims to provide practical advice and clinical considerations for working with [177Lu]Lu-PSMA-617; particularly, regarding the role of nurses in managing radiation safety, monitoring and reporting of adverse events, and counseling patients receiving this therapy.

Methods: Clinical data, protocols, and guidelines are summarized alongside real-world insights to provide practical recommendations for nurses caring for patients treated with [177Lu]Lu-PSMA-617.

Findings: Nurses coordinate safe care for patients receiving [177Lu]Lu-PSMA-617 by facilitating communication among physicians, managing logistic concerns, monitoring for adverse events related to treatment, providing education, and counseling patients and caregivers throughout treatment.

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[177Lu]Lu-PSMA-617治疗的实用指南，包括辐射安全、不良事件监测和患者咨询。

背景：前列腺特异性膜抗原（PSMA）靶向放射治疗[177Lu]Lu-PSMA-617的批准标志着转移性去势耐药前列腺癌症向精确医学治疗的转变。目的：本综述旨在为使用[177Lu]Lu-PSMA-617提供实用的建议和临床考虑；特别是关于护士在管理辐射安全、监测和报告不良事件以及咨询接受这种治疗的患者方面的作用。方法：总结临床数据、方案和指南以及真实世界的见解，为护理接受[177Lu]Lu-PSMA-617治疗的患者的护士提供实用建议。研究结果：护士通过促进医生之间的沟通、管理后勤问题、，监测与治疗相关的不良事件，在整个治疗过程中为患者和护理人员提供教育和咨询。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical journal of oncology nursing ONCOLOGY-NURSING

CiteScore

1.70

自引率

9.10%

发文量

127

审稿时长

6-12 weeks

期刊介绍： The Clinical Journal of Oncology Nursing (CJON) is an official publication of the Oncology Nursing Society (ONS) and is directed to the practicing nurse specializing in the care of patients with an actual or potential diagnosis of cancer. CJON is a vehicle to promote the mission of ONS, which is to advance excellence in oncology nursing and quality cancer care. The CJON mission is twofold: to provide practical information necessary to care for patients and their families across the cancer continuum and to develop publication skills in oncology nurses.