The assessment of thoracal approaches in the treatment of aortic coarctation.

IF 0.7 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Onur Işık, Gökmen Akkaya, Fatih Durak, Defne Engür, Meltem Çakmak, Ali Rahmi Bakiler, Muhammet Akyüz
{"title":"The assessment of thoracal approaches in the treatment of aortic coarctation.","authors":"Onur Işık,&nbsp;Gökmen Akkaya,&nbsp;Fatih Durak,&nbsp;Defne Engür,&nbsp;Meltem Çakmak,&nbsp;Ali Rahmi Bakiler,&nbsp;Muhammet Akyüz","doi":"10.5830/CVJA-2023-041","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The optimal choice of surgery in coarctation of the aorta (CoA) remains controversial but it needs to be individualised. However, in most conditions, a surgical approach through thoracotomy maintains adequate exposure to create aortic patency. This study aimed to assess the efficiency and reliability of thoracal approaches in the treatment of CoA by examining the mid- and late-term outcomes, and determining the predictive factors for re-intervention.</p><p><strong>Methods: </strong>Patients who underwent CoA repair through thoracotomy between September 2015 and February 2023 were included in the study, except for those with complex cardiac diseases. Medical records were retrospectively analysed and peri-operative course, follow-up findings on echocardiogram and physical examinations were obtained. The complication rate, postoperative arch gradient, need for antihypertensive medication use, and freedom from re-intervention were evaluated and then compared in terms of age at surgery.</p><p><strong>Results: </strong>Overall, 98 patients including 50 neonates were reviewed. The most common surgical method was extended end-to-end anastomosis, performed in 53 patients. The median follow-up time was 4.6 years. There was one death in hospital and one late mortality in the cohort. Eight complications were observed in the cohort but all recovered well. Overall, 13 re-interventions, six redo surgeries and seven balloon angioplasties were carried out in 12 patients. Ten of the re-interventions were carried out within the first year of the initial surgery. One- and three-year freedom from re-intervention rates were 89.5 and 86.4%, respectively. However, there was no significant predictive factor for re-intervention. Comparisons according to the age at surgery did not differ, except for intensive care unit stay. The need for hypertensive medication was initially in 14 (14.2%) patients and then reduced to eight (8%) patients. The mean peak residual gradient on postoperative examination was 9 mmHg.</p><p><strong>Conclusion: </strong>Thoracotomy provided feasible surgical access that led to satisfactory results with a low complication rate, negligible residual gradient, low incidence of hypertension and excellent rate for freedom from re-intervention in the treatment of CoA.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-6"},"PeriodicalIF":0.7000,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Journal of Africa","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5830/CVJA-2023-041","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: The optimal choice of surgery in coarctation of the aorta (CoA) remains controversial but it needs to be individualised. However, in most conditions, a surgical approach through thoracotomy maintains adequate exposure to create aortic patency. This study aimed to assess the efficiency and reliability of thoracal approaches in the treatment of CoA by examining the mid- and late-term outcomes, and determining the predictive factors for re-intervention.

Methods: Patients who underwent CoA repair through thoracotomy between September 2015 and February 2023 were included in the study, except for those with complex cardiac diseases. Medical records were retrospectively analysed and peri-operative course, follow-up findings on echocardiogram and physical examinations were obtained. The complication rate, postoperative arch gradient, need for antihypertensive medication use, and freedom from re-intervention were evaluated and then compared in terms of age at surgery.

Results: Overall, 98 patients including 50 neonates were reviewed. The most common surgical method was extended end-to-end anastomosis, performed in 53 patients. The median follow-up time was 4.6 years. There was one death in hospital and one late mortality in the cohort. Eight complications were observed in the cohort but all recovered well. Overall, 13 re-interventions, six redo surgeries and seven balloon angioplasties were carried out in 12 patients. Ten of the re-interventions were carried out within the first year of the initial surgery. One- and three-year freedom from re-intervention rates were 89.5 and 86.4%, respectively. However, there was no significant predictive factor for re-intervention. Comparisons according to the age at surgery did not differ, except for intensive care unit stay. The need for hypertensive medication was initially in 14 (14.2%) patients and then reduced to eight (8%) patients. The mean peak residual gradient on postoperative examination was 9 mmHg.

Conclusion: Thoracotomy provided feasible surgical access that led to satisfactory results with a low complication rate, negligible residual gradient, low incidence of hypertension and excellent rate for freedom from re-intervention in the treatment of CoA.

胸腔入路治疗主动脉缩窄的评价。
目的:主动脉缩窄(CoA)手术的最佳选择仍有争议,但需要个性化。然而,在大多数情况下,通过开胸手术的手术方法可以保持足够的暴露,以形成主动脉通畅。本研究旨在通过检查中晚期结果,并确定再干预的预测因素,评估经胸入路治疗CoA的有效性和可靠性。方法:2015年9月至2023年2月期间通过开胸手术接受CoA修复的患者被纳入研究,但患有复杂心脏病的患者除外。回顾性分析了医疗记录,并获得了围手术期的病程、超声心动图和体格检查的随访结果。评估并发症发生率、术后足弓梯度、是否需要降压药物以及是否免于再次干预,然后根据手术年龄进行比较。结果:共对98例患者(包括50例新生儿)进行了回顾性分析。最常见的手术方法是扩大端对端吻合,共有53名患者接受了手术。中位随访时间为4.6年。队列中有一例在医院死亡,一例晚期死亡。队列中观察到8例并发症,但均恢复良好。总共对12名患者进行了13次再干预、6次再手术和7次球囊血管成形术。其中10次再干预是在初次手术的第一年内进行的。一年和三年无再干预率分别为89.5%和86.4%。然而,再干预没有显著的预测因素。根据手术年龄进行的比较没有差异,除了重症监护室的住院时间。最初对高血压药物的需求为14名(14.2%)患者,后来减少到8名(8%)患者。术后检查的平均峰值残余梯度为9mmHg。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Cardiovascular Journal of Africa
Cardiovascular Journal of Africa CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.30
自引率
0.00%
发文量
0
审稿时长
4-8 weeks
期刊介绍: The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信