PLASMA 17-OHCS RESPONSE OF THE INFANT RHESUS MONKEY TO A NONINJURIOUS, NOXIOUS STIMULUS.

Abstract

Summary Two-day-old rhesus monkeys, restrained and rotated for one hour, exhibited elevations of 25.8 ± 3.3 (S.E.) μg% in plasma nonconjugated 17-OHCS. This sizable and consistent increase was 44% as great as the one hour increase in plasma nonconjugated 17-OHCS following ACTH, suggesting either that the restraint and rotation was not sufficiently stressful or that the infant CNS-hypophyseal axis was not sufficiently developed to stimulate fully the adrenal cortex.