Peroxisome proliferator-activated receptor γ

Rajbabu Pakala, Seung-Woon Rha, Pramod Kumar Kuchulakanti, Edouard Cheneau, Richard Baffour, Ron Waksman
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引用次数: 8

Abstract

Cellular proliferation and migration are fundamental processes that contribute to the injury response in major blood vessels. The resultant pathologies are atherosclerosis and restenosis. As we begin to understand the cellular changes associated with vascular injury, it is critical to determine whether the inhibition of growth and movement of cells in the vasculature could serve as a novel therapeutic strategy to prevent atherosclerosis and restenosis.

过氧化物酶体增殖物激活受体γ
细胞增殖和迁移是导致大血管损伤反应的基本过程。由此产生的病理是动脉粥样硬化和再狭窄。当我们开始了解与血管损伤相关的细胞变化时,确定抑制血管中细胞的生长和运动是否可以作为一种新的治疗策略来预防动脉粥样硬化和再狭窄是至关重要的。
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