ZINC CONTENT IN TISSUES OF PYRIDOXINE DEFICIENT RATS.

Abstract

Summary Pyridoxine deficiency in rats resulted in a decreased Zn content in the plasma, liver, pancreas, and heart tissues and an increase of Zn-65 uptake in the plasma and liver after an intramuscular injection of radiozinc. A highly significant increase in Zn-65 radioactivity was also observed in the gastrointestinal tract and feces of pyridoxine-deficient rats. This phenomenon appeared to be specific for pyridoxine since deficiency of thiamine or riboflavin did not affect hepatic Zn concentrations.