SUCCESSFUL IMMUNIZATION OF PRIMATES WITH RABIES VACCINE PREPARED IN HUMAN DIPLOID CELL STRAIN WI-38.

Abstract

Summary The antigenicity of 2 strains of rabies virus (Flury HEP and Pitman-Moore) propagated in a Human Diploid Cell Strain and used as live and inactivated vaccine was studied in Rhesus monkeys. It was found that these strains were much more antigenic than the same strains of virus propagated in embryonated avian egg before adaptation to tissue culture. The use of this tissue culture vaccine in man should be contemplated.