[Rapid Detection of Trace Enrofloxacin and Ciprofloxacin in Drinking Water by SERS].

Abstract

In recent years, the abuse of antibiotics has led to the spread and diffusion of antibiotic resistance genes in the environment, which poses a potential threat to the ecosystem and human health. In particular, the related reports of antibiotic contamination in drinking water have aroused great social concerns. Therefore, realizing the rapid detection of trace antibiotics in emergency events has become a research hotspot. Here, in combination with magnetic solid phase extraction (MSPE), we established a rapid detection strategy for ng·L^-1 level quinolones in drinking water using surface-enhanced Raman spectroscopy (SERS). With the help of the high enrichment capacity provided by the high adsorption capacity of the magnetic graphene oxide composite nanomaterial (Fe₃O₄@SiO₂-GO), the spiked detection of 1.0 ng·L^-1 enrofloxacin (ENR) and 5.0 ng·L^-1 ciprofloxacin (CIP) in drinking water was successfully achieved, with recoveries ranging from 77.5% to 91.5%, which met the current requirements of drinking water testing. For environmental water samples such as lake water, the selectivity of extraction materials needs to be further improved due to the strong interference of the complex organic matrix.