Tamir Bendory, Ariel Jaffe, William Leeb, Nir Sharon, Amit Singer
{"title":"Super-resolution multi-reference alignment.","authors":"Tamir Bendory, Ariel Jaffe, William Leeb, Nir Sharon, Amit Singer","doi":"10.1093/imaiai/iaab003","DOIUrl":null,"url":null,"abstract":"<p><p>We study super-resolution multi-reference alignment, the problem of estimating a signal from many circularly shifted, down-sampled and noisy observations. We focus on the low SNR regime, and show that a signal in <math> <mrow><msup><mi>ℝ</mi> <mi>M</mi></msup> </mrow> </math> is uniquely determined when the number <i>L</i> of samples per observation is of the order of the square root of the signal's length ( <math><mrow><mi>L</mi> <mo>=</mo> <mi>O</mi> <mo>(</mo> <msqrt><mi>M</mi></msqrt> <mo>)</mo></mrow> </math> ). Phrased more informally, one can square the resolution. This result holds if the number of observations is proportional to 1/SNR<sup>3</sup>. In contrast, with fewer observations recovery is impossible even when the observations are not down-sampled (<i>L</i> = <i>M</i>). The analysis combines tools from statistical signal processing and invariant theory. We design an expectation-maximization algorithm and demonstrate that it can super-resolve the signal in challenging SNR regimes.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374099/pdf/nihms-1776575.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1093/imaiai/iaab003","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/2/18 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
We study super-resolution multi-reference alignment, the problem of estimating a signal from many circularly shifted, down-sampled and noisy observations. We focus on the low SNR regime, and show that a signal in is uniquely determined when the number L of samples per observation is of the order of the square root of the signal's length ( ). Phrased more informally, one can square the resolution. This result holds if the number of observations is proportional to 1/SNR3. In contrast, with fewer observations recovery is impossible even when the observations are not down-sampled (L = M). The analysis combines tools from statistical signal processing and invariant theory. We design an expectation-maximization algorithm and demonstrate that it can super-resolve the signal in challenging SNR regimes.
我们研究的是超分辨率多参考对齐,即从许多圆周位移、下采样和噪声观测中估计信号的问题。我们将重点放在低信噪比机制上,并证明当每个观测点的采样数目为信号长度的平方根数量级(L = O ( M ))时,ℝ M 中的信号是唯一确定的。换个非正式的说法,我们可以将分辨率平方化。如果观测数据的数量与 1/SNR3 成正比,则这一结果成立。相反,如果观测值较少,即使观测值没有降低采样(L = M),也不可能恢复。分析结合了统计信号处理和不变理论的工具。我们设计了一种期望最大化算法,并证明它能在具有挑战性的信噪比情况下超级解译信号。
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.