Transforming Confocal Microscopy Imaging Data of Retinal Vasculature into 3D Animation.

The Journal of biocommunication Pub Date : 2022-06-04 eCollection Date: 2022-01-01 DOI:10.5210/jbc.v46i1.12636
Emilyn Frohn, Leah Lebowicz, Rex Twedt, Christine Young
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引用次数: 0

Abstract

This research study presents a methodology for creation of 3D models from confocal microscopy, specifically the retinal trilaminar capillary network, that can be used in 3D biomedical animation. Biomedical visualization professionals regularly use CT and MRI imaging data to create 3D models and other visuals. Adding confocal microscopy to this toolkit using ImageJ FIJI1 and Materialise Mimics® allows for a wider range of options to create data-driven 3D models of microscopic structures. Understanding the interactions of the neurovascular unit through visualization may be a key to advancing understanding of normal function of the retina and diabetic retinopathy pathology. This Vesalius Trust research poster was presented at the Association of Medical Illustrators' 2021 virtual annual meeting.

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将视网膜血管系统的共聚焦显微镜成像数据转化为三维动画。
本研究提出了一种从共聚焦显微镜创建3D模型的方法,特别是视网膜三层毛细血管网络,可用于3D生物医学动画。生物医学可视化专业人员经常使用CT和MRI成像数据来创建3D模型和其他视觉效果。使用ImageJ FIJI1和Materialise Mimics®将共聚焦显微镜添加到该工具包中,可以提供更广泛的选择,以创建数据驱动的微观结构3D模型。通过可视化了解神经血管单元的相互作用可能是促进视网膜正常功能和糖尿病视网膜病变病理理解的关键。这张维萨里乌斯信托研究海报在医学插画家协会2021年虚拟年会上展出。
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