Spectrum of Large- and Medium-Vessel Vasculitis in Adults: Neoplastic, Infectious, Drug-Induced, Autoinflammatory, and Primary Immunodeficiency Diseases.

IF 5.7 2区 医学 Q1 RHEUMATOLOGY
Current Rheumatology Reports Pub Date : 2022-10-01 Epub Date: 2022-08-03 DOI:10.1007/s11926-022-01083-5
Fabian Lötscher, Roxana Pop, Pascal Seitz, Mike Recher, Luca Seitz
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引用次数: 0

Abstract

Purpose of review: To provide a comprehensive review of drugs and neoplastic, infectious, autoinflammatory, and immunodeficiency diseases causing medium- to large-vessel vasculitis in adults with emphasis on information essential for the initial diagnostic process.

Recent findings: Entities with medium- to large-vessel vasculitis as clinical manifestations have been described recently (e.g., adenosine deaminase-2 deficiency, VEXAS-Syndrome), and vasculitis in established autoinflammatory or immunodeficiency diseases is increasingly being identified. In the diagnostic process of medium- to large-vessel vasculitis in adults, a large variety of rare diseases should be included in the differential diagnosis, especially if diagnosis is made without histologic confirmation and in younger patients. Although these disorders should be considered, they will undoubtedly remain rare in daily practice.

Abstract Image

成人大血管和中血管炎谱:肿瘤性、感染性、药物诱发、自身炎症和原发性免疫缺陷疾病。
综述目的:全面综述导致成人中大血管炎的药物和肿瘤性、感染性、自身炎症性和免疫缺陷性疾病,重点关注对初步诊断过程至关重要的信息:最近的研究结果:以中大血管炎为临床表现的实体(如腺苷脱氨酶-2缺乏症、VEXAS综合征)已在最近得到描述,而已确诊的自身炎症性疾病或免疫缺陷性疾病中的血管炎也越来越多地被发现。在成人中大静脉血管炎的诊断过程中,应将多种罕见疾病纳入鉴别诊断,尤其是在未经组织学确诊的情况下和年轻患者。尽管应该考虑这些疾病,但它们在日常实践中无疑仍然是罕见的。
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来源期刊
CiteScore
11.20
自引率
0.00%
发文量
41
期刊介绍: This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.
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