Diroximel fumarate for multiple sclerosis.

Abstract

Diroximel fumarate is another molecule that is rapidly hydrolysed to monomethyl fumarate after oral administration. Although food reduces the maximum concentration, capsules of diroximel fumarate can be taken with or without food. Most of the twicedaily dose is expired as carbon dioxide. No dose adjustments are recommended for patients with renal or hepatic impairment. Pharmacokinetic drug interactions are unlikely.