Survival Status and Predictors of Mortality Among Low Birthweight Neonates Admitted in Amhara Region Referral Hospitals of Ethiopia: Retrospective Follow-Up Study.

IF 1.5 Q3 HEALTH POLICY & SERVICES
Health Services Research and Managerial Epidemiology Pub Date : 2022-07-29 eCollection Date: 2022-01-01 DOI:10.1177/23333928221117364
Belete Fenta Kebede, Yalemtsehay Dagnaw Genie, Desta Hailu Aregawi, Behafta Afera Tadele
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引用次数: 0

Abstract

Background: Being born with low birthweight is a major determinant of perinatal, neonatal, and infant survival. Even though low birthweight-related neonatal mortality is high, there is an information gap regarding the survival status of low birthweight neonates and their predictors of mortality in Ethiopia.

Objective: This study was conducted to assess the survival status and predictors of mortality among low birthweight neonates admitted to Amhara region referral hospitals in Ethiopia.

Methods and materials: A retrospective follow-up study was conducted on randomly selected low birthweight neonates admitted to the Amhara region referral hospital between January 01-2017 and December 30-2018. Data were entered into Epi-data 4.4.2.1 and exported to Stata 14 for cleaning and analysis. A cox regression model was used to analyze the data. Tables, charts, and text were used to report the results.

Results: This study revealed that 35.2% of participants died with incidence rates of 37.86 per 1000 person-day observations (95%CI: 31.79-45.10). Sepsis (AHR:1.72(95% CI: 1.05-2.81), respiratory distress (AHR: 2.03 (95% CI:1.36-3.03), necrotizing enterocolitis (AHR: 2.47 (95% CI: 1.17-5.20), congenital anomalies (AHR:2.37 (95% CI: 1.36-4.13), extreme low birth weight (AHR:2.62 (95% CI:1.54-4.44) and prematurity (AHR: 2.55 (95% CI:1.10-5.92) were independent predictors of mortality.

Conclusion: Sepsis, respiratory distress, necrotizing enterocolitis, congenital anomalies, extremely low birth weight, and premature birth were the independent predictors of mortality. Therefore, it is better for all stakeholders to focus more on the early diagnosis and management of low birth weight neonates with the factors associated with mortality.

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埃塞俄比亚阿姆哈拉地区转诊医院低出生体重新生儿的生存状况和死亡率预测因素:回顾性随访研究
背景:低出生体重是围产期、新生儿和婴儿存活率的主要决定因素。尽管与低出生体重相关的新生儿死亡率很高,但在埃塞俄比亚,低出生体重新生儿的生存状况及其死亡率预测因素方面存在信息缺口。目的:本研究旨在评估埃塞俄比亚阿姆哈拉地区转诊医院收治的低出生体重新生儿的生存状况和死亡率预测因素。方法与材料:随机选取2017年1月1日至2018年12月30日在阿姆哈拉地区转诊医院住院的低出生体重新生儿进行回顾性随访研究。数据输入Epi-data 4.4.2.1,导出到Stata 14进行清理和分析。采用cox回归模型对数据进行分析。使用表格、图表和文本来报告结果。结果:该研究显示,35.2%的参与者死亡,每1000人日观察的发病率为37.86 (95%CI: 31.79-45.10)。脓毒症(AHR:1.72(95% CI: 1.05-2.81)、呼吸窘迫(AHR: 2.03 (95% CI:1.36-3.03)、坏死性小肠结肠炎(AHR: 2.47 (95% CI: 1.17-5.20)、先天性异常(AHR:2.37 (95% CI: 1.36-4.13)、极低出生体重(AHR:2.62 (95% CI:1.54-4.44)和早产(AHR: 2.55 (95% CI:1.10-5.92)是死亡率的独立预测因素。结论:脓毒症、呼吸窘迫、坏死性小肠结肠炎、先天性异常、极低出生体重和早产是死亡率的独立预测因素。因此,所有利益相关方最好更多地关注与死亡相关因素的低出生体重新生儿的早期诊断和管理。
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来源期刊
CiteScore
1.60
自引率
6.20%
发文量
32
审稿时长
12 weeks
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