Ovarian Cancer Metastasis to the Central Nervous System: A Literature Review.

Arnav Barpujari, Elizabeth Klaas, Jeffery Roberts, Kim-Anh Vo, Esaan Azizi, Melanie Martinez, Eric Sung, Brandon Lucke-Wold
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Abstract

Ovarian cancer is one of the leading causes of cancer-related deaths among women in the United States. Metastasis to the central nervous system has become more frequent in the previous decades, however, treatment options remain limited. In this review, we discuss the pathophysiology of ovarian cancer and how metastasis to the central nervous system typically occurs. We then discuss cases of metastasis presented in the literature to evaluate current treatment regimens and protocols. Finally, we highlight emerging treatment options that are being utilized in clinics to provide personalized treatment therapy for a patient's unique diagnosis. This review aims to further the understanding of pathophysiology, stimulate further innovative treatments, and present accessible resources through tables and figures.

Abstract Image

Abstract Image

卵巢癌转移至中枢神经系统:文献综述。
卵巢癌是美国妇女因癌症死亡的主要原因之一。在过去的几十年中,向中枢神经系统转移的情况越来越频繁,但治疗方案仍然有限。在这篇综述中,我们将讨论卵巢癌的病理生理学以及中枢神经系统转移是如何发生的。然后,我们讨论文献中介绍的转移病例,以评估当前的治疗方案。最后,我们重点介绍了临床上正在使用的新兴治疗方案,以针对患者的独特诊断提供个性化治疗。这篇综述旨在进一步加深对病理生理学的理解,激发更多的创新治疗方法,并通过表格和图表介绍可获取的资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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