What to Know About Biopsy Sampling and Pathology in Vasculitis?

IF 5.7 2区医学 Q1 RHEUMATOLOGY

Current Rheumatology Reports Pub Date : 2022-09-01 Epub Date: 2022-07-27 DOI:10.1007/s11926-022-01082-6

Chiara Marvisi, Francesco Muratore, Chiara Cabassi, Elena Galli, Luigi Boiardi, Simonetta Piana, Maria Cecilia Mengoli, Carlo Salvarani, Alberto Cavazza

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引用次数: 2

Abstract

Purpose of review: To summarize the histologic findings of vasculitis, and to give some practical considerations on biopsy samples.

Recent findings: The larger use of imaging and the discoveries of serological markers in the diagnosis of vasculitis have increased the clinical recognition of these entities. Nevertheless, biopsy remains the gold standard for diagnosis in most cases. So far, biopsies are also useful to obtain information about prognosis and to guide a more specific treatment. In recent years, less invasive diagnostic approaches have become available, lowering the risks related to the procedure and permitting a definite diagnosis in most cases. Histological examination permits a definite diagnosis of vasculitis. However, the findings may be nonspecific if not evaluated in the proper clinical setting. The interaction between clinicians and pathologists is crucial to obtain a definite diagnosis.

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关于血管炎的活检和病理需要知道些什么?

综述目的:总结血管炎的组织学表现，并对活检标本提出一些实际考虑。最近的发现:影像学的广泛应用和血清学标志物在血管炎诊断中的发现增加了对这些实体的临床认识。然而，在大多数情况下，活检仍然是诊断的金标准。到目前为止，活组织检查对于获得预后信息和指导更具体的治疗也很有用。近年来，侵入性较小的诊断方法已经可用，降低了与手术相关的风险，并在大多数情况下允许明确的诊断。组织学检查可明确诊断血管炎。然而，如果没有在适当的临床环境中评估，结果可能是非特异性的。临床医生和病理学家之间的互动对于获得明确的诊断至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Rheumatology Reports RHEUMATOLOGY-

CiteScore

11.20

自引率

0.00%

发文量

期刊介绍： This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.