Efficiency of Diagnostic Test for SARS-CoV-2 in a Nursing Home.

IF 2.1
Sergio Salmerón, Alonso López-Escribano, Inmaculada García-Nogueras, Joaquina Lorenzo, Juan Manuel Romero, Antonio Hernández-Martínez, Francisco García-Alcaraz
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Abstract

Background: there is no consensus on how to optimally use diagnostic tests in each stage of COVID-19 pandemic. The objective of this research is to determine the efficiency of sorting positive antibody test quarterly.

Methods: this research uses a retrospective, observational study. COVID-19 diagnostic tests performed and avoided refer to a Spanish nursing home.

Population: 261 employees and 107 residents. A quarterly antibody test was performed on subjects who had tested positive during the first wave of coronavirus, and a antibody rapid test on the remaining subjects.

Results: during the first wave, 24.0% of the employees and 51.4% of the residents had a positive antibody test. Seronegativization was observed in 7.6% of employees and 1.6% of residents. An employee was infected with COVID-19 in September 2020, followed by a nursing home outbreak in October: 118 Polymerase Chain Reactions tests were avoided in residents and 18 in employees, which in turn prevented 15 workers from going on sick leave and the quarantine of 59 residents. This represents savings of about $15,000.

Conclusions: our study supports the need to know and apply the strategies for early detection, surveillance and control of COVID-19 for future outbreaks. We conclude that surveillance for positive COVID-19 serology among long-term care staff and residents may be a cost-effective strategy during a pandemic.

Abstract Image

Abstract Image

某养老院SARS-CoV-2诊断检测效果分析
背景:如何在COVID-19大流行的每个阶段最佳地使用诊断检测尚未达成共识。本研究的目的是确定每季阳性抗体检测的分选效率。方法:本研究采用回顾性观察性研究。进行和避免的COVID-19诊断测试转介到西班牙养老院。人口:职工261人,居民107人。对第一波冠状病毒检测呈阳性的受试者进行季度抗体检测,对其余受试者进行抗体快速检测。结果:第一波工作人员抗体阳性率为24.0%,居民抗体阳性率为51.4%。7.6%的员工和1.6%的居民血清阴性。2020年9月,一名员工感染了COVID-19,随后10月养老院爆发了疫情:居民避免了118次聚合酶链反应测试,员工避免了18次测试,从而避免了15名工人请病假和59名居民被隔离。这相当于节省约15 000美元。结论:我们的研究支持有必要了解和应用COVID-19早期发现、监测和控制策略,以应对未来的疫情。我们的结论是,在大流行期间,对长期护理人员和居民进行COVID-19血清学阳性监测可能是一种具有成本效益的策略。
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