Helga Moura Kehrle, Ronaldo Campos Granjeiro, Andre Luiz L Sampaio, Maria Stella de Farias, Vaneli Silva Martins, Carlos Augusto C P de Oliveira
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引用次数: 2
Abstract
Objective: To describe the natural history of tinnitus in normal hearing patients.
Study design: This is a prospective longitudinal observational study.
Setting: Tertiary University Hospital.
Methods: In 2009 we studied 68 patients with significant tinnitus and normal hearing (Study Group-SG) compared to 46 patients with normal hearing and no tinnitus (Control Group-CG). We have been able to contact and recruit 24 patients from SG (35.3 %) and ten patients from CG) (21.74%) in 2019. Both groups were submitted to conventional audiometry, Distortion Product Otoacoustic Emissions (DPOAE), Tinnitus Handicap Inventory (THI), Visual Analog Scale (VAS) and Beck`S Depression and Anxiety Scales (BDS, BAS). These measures were compared with the same ones performed ten years ago in the same groups of patients. The software SPSS for windows version 21 was used. P values <0.05 were considered significant. Student t test was used to compare SG and CG results in 2019 and to compare 2009 and 2019 outcomes..
Results: Hearing loss, especially in the higher frequencies, were significantly worse in SG compared to GC in 2019. DPOAE were significantly worse in SG and CG in 2019 however CG had more abnormal results than SG. These results suggest that outer hair cells lesions are not the only determinant for tinnitus and hearing loss development.
Conclusions: These results suggest that outer hair cells lesions are not the only determinant for tinnitus and hearing loss development.
目的:探讨听力正常患者耳鸣的自然病程。研究设计:这是一项前瞻性纵向观察研究。单位:第三大学附属医院。方法:2009年,我们将68例听力正常的耳鸣患者(sg组)与46例听力正常无耳鸣患者(cg组)进行比较。2019年,我们已经联系并招募了24名SG患者(35.3%)和10名CG患者(21.74%)。两组均接受常规听力学测试、畸变产物耳声发射(DPOAE)、耳鸣障碍量表(THI)、视觉模拟量表(VAS)和贝克抑郁焦虑量表(BDS, BAS)。这些测量与十年前在同一组患者中进行的相同测量进行了比较。采用SPSS for windows version 21软件。结果:2019年,SG组听力损失,尤其是高频听力损失,明显高于GC组。2019年SG和CG的DPOAE明显加重,但CG的异常结果多于SG。这些结果表明,外毛细胞损伤并不是耳鸣和听力损失发展的唯一决定因素。结论:这些结果表明外毛细胞损伤不是耳鸣和听力损失发展的唯一决定因素。
期刊介绍:
The International Tinnitus Journal is the first peer review journal to provide a forum for exchange of information of on-going basic and clinical science efforts for understanding tinnitus and its application to patient diagnosis and treatment. Subject areas to be covered range from fundamental theory to clinical applications.