[Prevalence and genotypes of cervical and vaginal HPV in female sex workers attending a Sexual Control Centre, North Area of Santiago, Chile].

IF 0.4 4区医学 Q4 INFECTIOUS DISEASES

Revista Chilena De Infectologia Pub Date : 2022-04-01 DOI:10.4067/S0716-10182022000200117

Karla Hott-Schulz, Eugenio Ramírez-Villalobos, Macarena Ortega-Peña, Ester Santander-Cabello, Javier Fernández-Moraga, Viviana Zemelman-Decarli, Claudia Correa-Soza

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引用次数: 0

Abstract

Background: In Chile, cervical cancer is the second leading cause of death from malignancy in women. The main causal agent of cervical cancer is the human papillomavirus (HPV). Compared with the general population, sex workers (SW) are at increased risk of acquiring HPV.

Aim: To analyze the prevalence and genotypes of cervical and vaginal HPV in female SW attending a Sexual Control Centre.

Methods: A cross-sectional study was carried out on 97 women (19-70 years old). Two samples were taken per patient, one from exocervix and the other from vaginal walls. HPV DNA. was identified by polymerase chain reaction (PCR) and genotyping using specific probes for 32 types of HPV.

Results: The overall frequency of HPV was 45%, 41.2% in cervical carrier and 36.1% in vaginal carrier, 32% were co-infected, 63% of HPV were high-risk genotypes. The most frequent high-risk HPV was HPV 66 (12%), HPV 58 (9.3%), followed by HPV 16, HPV 59 and HPV 82 with the same frequency (8% each one). Thirty two (43%) of females were infected with multiple genotypes.

Conclusion: HPV is frequent infection among SW. This is the first study in Chile on the prevalence and genotypes of HPV in sex workers.

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[在智利圣地亚哥北部地区性控制中心就诊的女性性工作者中宫颈和阴道HPV的患病率和基因型]。

背景:在智利，子宫颈癌是妇女恶性肿瘤死亡的第二大原因。宫颈癌的主要致病因子是人乳头瘤病毒(HPV)。与一般人群相比，性工作者(SW)感染HPV的风险更高。目的:分析在性控制中心就诊的女性SW患者宫颈和阴道HPV的患病率和基因型。方法:对97例19 ~ 70岁女性进行横断面研究。每位患者取两份样本，一份取自外宫颈，另一份取自阴道壁。人乳头状瘤病毒DNA。采用聚合酶链反应(PCR)和特异性探针对32型HPV进行基因分型鉴定。结果:HPV总检出率为45%，宫颈检出率为41.2%，阴道检出率为36.1%，合并感染32%，高危基因型占63%。最常见的高危HPV是HPV 66(12%)、HPV 58(9.3%)，其次是HPV 16、HPV 59和HPV 82，频率相同(各占8%)。32名(43%)女性感染多基因型。结论:人乳头状瘤病毒是西南偏南人群的常见病。这是智利第一个关于性工作者中HPV患病率和基因型的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Chilena De Infectologia 医学-传染病学

CiteScore

0.90

自引率

20.00%

发文量

审稿时长

4-8 weeks

期刊介绍： La Revista Chilena de Infectología publica artículos en español sobre Infectología latinoamericana. Los propósitos de nuestra revista son: Difundir la experiencia nacional y latinoamericana en la especialidad Divulgar la doctrina de la Sociedad Chilena de Infectología (SOCHINF) sobre el adecuado uso de los recursos diagnósticos, terapéuticos y preventivos de infecciones. Las temáticas que cubre la revista son: Antimicrobianos Epidemiología de Infecciones Infecciones de la Comunidad o Asociadas a la Atención de Salud Infecciones en Hospederos Inmunocomprometidos Microbiología Parasitología Patogénesis VIH Vacunas.