Clinico-Epidemiological Characteristics of Healthcare Workers with SARS-CoV-2 Infection during the First and Second Waves in a Teaching Hospital from Eastern India: A Comparative Analysis.

Q2 Medicine

Hospital Topics Pub Date : 2024-04-01 Epub Date: 2022-07-19 DOI:10.1080/00185868.2022.2096523

Arvind Kumar Singh, Manoj Kumar Panigrahi, Somen Kumar Pradhan, Debkumar Pal, Sonu H Subba, Binod Kumar Patro, Binod Kumar Behera, Baijayantimala Mishra, Bijayini Behera, Prasanta Raghab Mohapatra, Sourin Bhuniya, Shakti Kumar Bal, Saurav Sarkar, Jawahar S K Pillai, Sachidananda Mohanty, Batmanabane Gitanjali

{"title":"Clinico-Epidemiological Characteristics of Healthcare Workers with SARS-CoV-2 Infection during the First and Second Waves in a Teaching Hospital from Eastern India: A Comparative Analysis.","authors":"Arvind Kumar Singh, Manoj Kumar Panigrahi, Somen Kumar Pradhan, Debkumar Pal, Sonu H Subba, Binod Kumar Patro, Binod Kumar Behera, Baijayantimala Mishra, Bijayini Behera, Prasanta Raghab Mohapatra, Sourin Bhuniya, Shakti Kumar Bal, Saurav Sarkar, Jawahar S K Pillai, Sachidananda Mohanty, Batmanabane Gitanjali","doi":"10.1080/00185868.2022.2096523","DOIUrl":null,"url":null,"abstract":"In this retrospective observational study, we have performed a comparative analysis of the demographic, clinical and epidemiological characteristics of the HCWs affected with SARS-CoV-2 infection during first two waves in India. The overall prevalence of SARS-CoV-2 infection among HCWs was found to be 15.24% (14.20-16.33) and 23.38% (22.14-25.65) during first and second waves respectively. The second wave showed an adjusted odds ratio of 0.04(0.02-0.07) and 2.09(1.49-2.93) for hospitalization and being symptomatic, respectively. We detected significantly higher level of C-reactive protein (CRP) among admitted HCWs during the second wave (5.10 -14.60 mg/dl) as compared to the first wave (2.00 - 2.80 mg/dl). Our study found the relative risk of SARS-CoV-2 reinfection among HCWs during the second wave to be 0.68 [0.57-0.82, p < 0.001)]. Although, the prevalence of SARS CoV-2 infection and risk of being symptomatic was higher during second wave, the risk of hospitalization was less when compared with the first wave.","PeriodicalId":55886,"journal":{"name":"Hospital Topics","volume":" ","pages":"84-95"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital Topics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/00185868.2022.2096523","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/7/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

In this retrospective observational study, we have performed a comparative analysis of the demographic, clinical and epidemiological characteristics of the HCWs affected with SARS-CoV-2 infection during first two waves in India. The overall prevalence of SARS-CoV-2 infection among HCWs was found to be 15.24% (14.20-16.33) and 23.38% (22.14-25.65) during first and second waves respectively. The second wave showed an adjusted odds ratio of 0.04(0.02-0.07) and 2.09(1.49-2.93) for hospitalization and being symptomatic, respectively. We detected significantly higher level of C-reactive protein (CRP) among admitted HCWs during the second wave (5.10 -14.60 mg/dl) as compared to the first wave (2.00 - 2.80 mg/dl). Our study found the relative risk of SARS-CoV-2 reinfection among HCWs during the second wave to be 0.68 [0.57-0.82, p < 0.001)]. Although, the prevalence of SARS CoV-2 infection and risk of being symptomatic was higher during second wave, the risk of hospitalization was less when compared with the first wave.

查看原文本刊更多论文

印度东部一家教学医院第一波和第二波期间感染 SARS-CoV-2 的医护人员的临床流行病学特征：比较分析。

在这项回顾性观察研究中，我们对印度前两次感染 SARS-CoV-2 的高危工人的人口统计、临床和流行病学特征进行了比较分析。研究发现，在第一波和第二波中，感染 SARS-CoV-2 的医护人员的总发病率分别为 15.24% (14.20-16.33)和 23.38% (22.14-25.65)。第二波显示，住院和有症状的调整后几率分别为 0.04（0.02-0.07）和 2.09（1.49-2.93）。我们发现，与第一波（2.00 - 2.80 mg/dl）相比，第二波（5.10 - 14.60 mg/dl）中入院的高危产妇的 C 反应蛋白（CRP）水平明显更高。我们的研究发现，第二波人机工程人员再次感染 SARS-CoV-2 的相对风险为 0.68 [0.57-0.82, p 0.001)]。虽然第二波感染 SARS CoV-2 的流行率和出现症状的风险较高，但与第一波相比，住院风险较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Hospital Topics Medicine-Medicine (all)

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Hospital Topics is the longest continuously published healthcare journal in the United States. Since 1922, Hospital Topics has provided healthcare professionals with research they can apply to improve the quality of access, management, and delivery of healthcare. Dedicated to those who bring healthcare to the public, Hospital Topics spans the whole spectrum of healthcare issues including, but not limited to information systems, fatigue management, medication errors, nursing compensation, midwifery, job satisfaction among managers, team building, and bringing primary care to rural areas. Through articles on theory, applied research, and practice, Hospital Topics addresses the central concerns of today"s healthcare professional and leader.