Prophylactic Radiotherapy for Prevention of Heterotopic Ossification After Periacetabular Fractures: A Review of Efficacy and Associated Conditions.

Journal of surgical orthopaedic advances Pub Date : 2022-01-01

Joseph S Geller, Paul R Allegra, Crystal S Seldon, Benjamin O Spieler, Lara L Cohen, Spencer W Barnhill, Samuel R Huntley, Stuart Samuels, Lora Wang, Derek Isrow, Alberto De La Zerda, Aaron H Wolfson, Giselle Hernandez, Fernando E Vilella, Raphael L Yechieli

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Abstract

Prophylactic radiotherapy (XRT) is a commonly used treatment to decrease heterotopic ossification (HO) in patients with traumatic hip injuries. We conducted a retrospective review of patients at risk for HO who underwent XRT. Of the patients reviewed, 27.3% developed radiographic HO, 11.2% developed symptoms, and 2.0% required resection surgery. Patients were divided into primary (n = 71) and secondary prophylaxis (n = 27) cohorts. In the primary group, 25.0% developed radiographic HO, 5.6% developed symptoms, and 0 required surgery. In the secondary cohort, 33.3% of patients developed new radiographic HO, and 25.9% were symptomatic: four had a Brooker score of 3, and three had a score of 4 (p = 0.03), and 7.4% required surgical resection. (Journal of Surgical Orthopaedic Advances 31(2):113-118, 2022).

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预防性放疗预防髋臼周围骨折后异位骨化:疗效和相关条件的综述。

预防性放射治疗(XRT)是减少外伤性髋关节损伤患者异位骨化(HO)的常用治疗方法。我们对接受XRT治疗的有HO风险的患者进行了回顾性研究。在回顾的患者中，27.3%的患者出现了影像学上的HO, 11.2%的患者出现了症状，2.0%的患者需要切除手术。患者被分为初级队列(n = 71)和二级预防队列(n = 27)。在原发性组中，25.0%的患者出现了影像学上的HO, 5.6%的患者出现了症状，0例患者需要手术治疗。在第二队列中，33.3%的患者出现了新的放射学HO, 25.9%的患者出现症状:4名患者的Brooker评分为3分，3名患者的评分为4分(p = 0.03)， 7.4%的患者需要手术切除。[j] .外科骨科进展，31(2):113- 118,2022。

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Journal of surgical orthopaedic advances

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