Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma.

Pub Date : 2022-06-30 eCollection Date: 2022-04-01 DOI:10.1055/s-0042-1749423
Sweety Gupta, Gaurav Sharma, Nidhi Sharma, Shreyosi Mandal, Amit Gupta, Manoj Gupta
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Abstract

Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented with umbilical mass, but the primary could not be localized even after thorough investigations and work up. Also, there existed therapeutic dilemma because immunohistochemistry did not favor one site, and so he was considered for combination chemotherapy in view of unresectable disease.

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原发灶不明的脐带结节转移:诊断与治疗的难题。
脐带结节转移并不是原发灶不明癌症的常见表现。它可能是原发性恶性肿瘤的首发症状,也可能是既往诊断癌症的转移部位,被认为是预后不良的发现。我们在此报告了一例年轻男性脐部肿块病例,经过全面检查和治疗后,仍无法确定原发肿瘤的位置。此外,由于免疫组化并不倾向于某一部位,因此在治疗上存在两难选择,考虑到无法切除的疾病,他被考虑接受联合化疗。
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