Severe Hyperprolactinemia during Lurasidone Treatment in a 16-year Old Girl with Schizophrenia - A Case Report.

IF 1.4 Q3 PSYCHIATRY

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology Pub Date : 2022-07-03 eCollection Date: 2022-01-01 DOI:10.2478/sjcapp-2022-0009

Karsten Gjessing Jensen

{"title":"Severe Hyperprolactinemia during Lurasidone Treatment in a 16-year Old Girl with Schizophrenia - A Case Report.","authors":"Karsten Gjessing Jensen","doi":"10.2478/sjcapp-2022-0009","DOIUrl":null,"url":null,"abstract":"Background: Increase of serum prolactin is a common adverse effect to antipsychotic medication, potentially leading to galactorrhea, menstrual cycle disturbances or sexual adverse effects. Lurasidone is commonly associated with a low risk of prolactin change.Objective: To describe a case of severe hyperprolactinemia in a 16-year old female with schizophrenia.Method: Case report.Results: We saw a severe and sustained prolactin increase during treatment with lurasidone.Conclusions: Although lurasidone is usually considered not to increase prolactin, some patients may experience this adverse effect. As related subjective consequences may be falsely attributed to the disease or as direct effects of the antipsycotic agent, serum prolactin measurements should be made prior to and during antipsychotic treatment regardless of medication choice.","PeriodicalId":42655,"journal":{"name":"Scandinavian Journal of Child and Adolescent Psychiatry and Psychology","volume":" ","pages":"87-88"},"PeriodicalIF":1.4000,"publicationDate":"2022-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/dd/sjcapp-10-087.PMC9284940.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Child and Adolescent Psychiatry and Psychology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/sjcapp-2022-0009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Increase of serum prolactin is a common adverse effect to antipsychotic medication, potentially leading to galactorrhea, menstrual cycle disturbances or sexual adverse effects. Lurasidone is commonly associated with a low risk of prolactin change.

Objective: To describe a case of severe hyperprolactinemia in a 16-year old female with schizophrenia.

Method: Case report.

Results: We saw a severe and sustained prolactin increase during treatment with lurasidone.

Conclusions: Although lurasidone is usually considered not to increase prolactin, some patients may experience this adverse effect. As related subjective consequences may be falsely attributed to the disease or as direct effects of the antipsycotic agent, serum prolactin measurements should be made prior to and during antipsychotic treatment regardless of medication choice.

查看原文本刊更多论文

16岁精神分裂症女孩鲁拉西酮治疗期间严重高泌乳素血症1例报告。

背景:血清催乳素升高是抗精神病药物的常见不良反应，可能导致溢乳、月经周期紊乱或性不良反应。鲁拉西酮通常与低风险的催乳素变化有关。目的:报告1例16岁女精神分裂症患者重度高泌乳素血症。方法:病例报告。结果:在鲁拉西酮治疗期间，我们观察到严重且持续的催乳素升高。结论:虽然鲁拉西酮通常被认为不会增加催乳素，但一些患者可能会出现这种不良反应。由于相关的主观后果可能被错误地归因于疾病或作为抗精神病药物的直接影响，无论药物选择如何，在抗精神病药物治疗之前和期间都应测量血清催乳素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology PSYCHIATRY-

自引率

5.30%

发文量

审稿时长

8 weeks