Integrated use of laboratory services for multiple infectious diseases in the WHO European Region during the COVID-19 pandemic and beyond.

Daniel Simões, Soudeh Ehsani, Maja Stanojevic, Natalia Shubladze, Gulmira Kalmambetova, Roger Paredes, Daniela Maria Cirillo, Ana Avellon, Irina Felker, Florian P Maurer, Askar Yedilbayev, Francis Drobniewski, Lara Vojnov, Anne S Johansen, Nicole Seguy, Masoud Dara
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Abstract

Technical advances in diagnostic techniques have permitted the possibility of multi-disease-based approaches for diagnosis and treatment monitoring of several infectious diseases, including tuberculosis (TB), human immunodeficiency virus (HIV), viral hepatitis and sexually transmitted infections (STI). However, in many countries, diagnosis and monitoring, as well as disease response programs, still operate as vertical systems, potentially causing delay in diagnosis and burden to patients and preventing the optimal use of available resources. With countries facing both human and financial resource constraints, during the COVID-19 pandemic even more than before, it is important that available resources are used as efficiently as possible, potential synergies are leveraged to maximise benefit for patients, continued provision of essential health services is ensured. For the infectious diseases, TB, HIV, hepatitis C (HCV) and STI, sharing devices and integrated services starting with rapid, quality-assured, and complete diagnostic services is beneficial for the continued development of adequate, efficient and effective treatment strategies. Here we explore the current and future potential (as well as some concerns), importance, implications and necessary implementation steps for the use of platforms for multi-disease testing for TB, HIV, HCV, STI and potentially other infectious diseases, including emerging pathogens, using the example of the COVID-19 pandemic.

世卫组织欧洲区域在2019冠状病毒病大流行期间及之后综合使用多种传染病的实验室服务。
诊断技术的技术进步使多种基于疾病的方法有可能用于诊断和监测几种传染病,包括结核病、人体免疫缺陷病毒、病毒性肝炎和性传播感染。然而,在许多国家,诊断和监测以及疾病应对规划仍然作为垂直系统运作,可能造成诊断延误和患者负担,并阻碍现有资源的最佳利用。鉴于各国在2019冠状病毒病大流行期间比以往更加面临人力和财政资源的限制,必须尽可能有效地利用现有资源,利用潜在的协同效应,最大限度地为患者带来利益,并确保持续提供基本卫生服务。对于结核病、艾滋病毒、丙型肝炎(HCV)和性传播感染等传染病,从快速、有质量保证和完整的诊断服务开始共享设备和综合服务,有利于继续制定充分、高效和有效的治疗战略。在这里,我们以COVID-19大流行为例,探讨使用结核病、艾滋病毒、丙型肝炎病毒、性传播感染和其他潜在传染病(包括新出现的病原体)的多病检测平台的当前和未来潜力(以及一些问题)、重要性、影响和必要的实施步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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