Survival analysis and outcome prediction of COVID-19 patients: a retrospective observational study from tertiary referral hospital in Indonesia.

IF 0.8 4区医学 Q4 PARASITOLOGY

Tropical biomedicine Pub Date : 2022-06-01 DOI:ttps://doi.org/10.47665/tb.39.2.013

V Visuddho, A Subagjo, R A Setyoningrum, A N Rosyid

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引用次数: 0

Abstract

Coronavirus Disease 2019 (COVID-19) pandemic has become a global concern. Recently, Indonesia contributed the third-highest number of new COVID-19 cases in the world. We provide supporting information for COVID-19 management. This retrospective cohort study was conducted at Dr. Soetomo General Hospital. Researchers collected demographics, comorbidity, initial laboratory tests, and complications data of patients. This study performed a comparative, survival, and Receiver Operating Characteristic (ROC) curve analysis. Survival analysis showed a decrease in the probability of survival associated with an increase in the variables of age, diabetes, white blood cell (WBC) count, and neutrophils percentage, and a decrease in lymphocytes percentage during hospitalization. Lymphocyte percentage, neutrophil-lymphocyte ratio (NLR), WBC count, neutrophil percentage, had an accuracy 0.727 (95%CI 0.642-0.812; p<0.001), 0.726 (95%CI 0.641-0.812; p<0.001), 0.706 (95%CI 0.615-0.796; p<0.001), and 0.700 (95%CI 0.612-0.788; p<0.001) respectively, in predicting worse outcome. Our study suggests routine complete blood count tests in the admission of a patient with COVID-19 infections, which can be used to determine the survival and prognosis of hospitalized patients.

查看原文本刊更多论文

COVID-19患者的生存分析和预后预测:来自印度尼西亚三级转诊医院的回顾性观察研究

2019冠状病毒病(COVID-19)大流行已成为全球关注的问题。最近，印度尼西亚的新冠肺炎病例数量在世界上排名第三。我们为COVID-19管理提供支持信息。这项回顾性队列研究在Dr. Soetomo总医院进行。研究人员收集了患者的人口统计、合并症、初始实验室检查和并发症数据。本研究进行了比较、生存和受试者工作特征(ROC)曲线分析。生存分析显示，住院期间，年龄、糖尿病、白细胞(WBC)计数、中性粒细胞百分比和淋巴细胞百分比的增加与生存概率的降低有关。淋巴细胞百分率、中性粒细胞与淋巴细胞比值(NLR)、白细胞计数、中性粒细胞百分率，准确率为0.727 (95%CI 0.642 ~ 0.812;p

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来源期刊

Tropical biomedicine 医学-寄生虫学

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Society publishes the Journal – Tropical Biomedicine, 4 issues yearly. It was first started in 1984. The journal is now abstracted / indexed by Medline, ISI Thompson, CAB International, Zoological Abstracts, SCOPUS. It is available free on the MSPTM website. Members may submit articles on Parasitology, Tropical Medicine and other related subjects for publication in the journal subject to scrutiny by referees. There is a charge of US$200 per manuscript. However, charges will be waived if the first author or corresponding author are members of MSPTM of at least three (3) years'' standing.