[Granulomatous hypersensitivity angiitis of Churg and Strauss's syndrome : favorable outcome in one case].

Abstract

A further case of granulomatous hypersensitivity angiitis (syndrome described by Churg and Strauss) is reported. Clinical, biological, and histological features (asthma, blood eosinophilia, necrotizing angiitis lesions, extravascular eosinophilic and granulomatous infiltrates) differentiate this affection from other necrotizing angiitis diseases, particularly from polyarteritis nodosa. Unusual features in this case were its favorable course, and the remission following combined corticoid and cyclophosphamide treatment. Diagnostic, clinical and histological criteria which distinguish Churg and Strauss's angiitis from other necrotizing angiitis affections are described, and current pathogenic hypotheses discussed.