Laura Spruit, Deborah Bell, Tyler Brown, Katie O'Flanherty, Dana Lombardi, Rod Handy, Jennifer Coombs
{"title":"COVID-19 severity in people living with HIV: A pilot study in the Rocky Mountain West.","authors":"Laura Spruit, Deborah Bell, Tyler Brown, Katie O'Flanherty, Dana Lombardi, Rod Handy, Jennifer Coombs","doi":"10.1097/01.JAA.0000892860.04492.40","DOIUrl":null,"url":null,"abstract":"At the start of this research, COVID-19 accounted for more than 110 million cases worldwide and 2.4 million deaths. Utah had 369,433 confi rmed cases, 14,597 hospi-talizations, and 1,890 deaths. Early research showed that patients with immunocompromise were at greater risk for developing more severe COVID-19 illness. This study investigated patients with HIV and their immunocompro-mised state (based on CD4 count and the presence of comorbidities) to better predict the severity of COVID-19. P = .66, df = 4. Chi -square analysis for the acute illness severity score compared with CD4 count resulted in a chi -square of 4.53, P = .33, df = 4. Both P values were greater than the desired P value of less than 0.05. The chi -square analysis suggested that no statistical signifi cance existed between the number of comorbidities and the severity of acute illness or CD4 count. Scatter plot regression was performed between the variables, and the R2 suggested no correlation between severity of acute illness and number of comorbidities or CD4 count closest to time of diagnosis of COVID-19.","PeriodicalId":520655,"journal":{"name":"JAAPA : official journal of the American Academy of Physician Assistants","volume":" ","pages":"1"},"PeriodicalIF":0.8000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JAAPA : official journal of the American Academy of Physician Assistants","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/01.JAA.0000892860.04492.40","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
At the start of this research, COVID-19 accounted for more than 110 million cases worldwide and 2.4 million deaths. Utah had 369,433 confi rmed cases, 14,597 hospi-talizations, and 1,890 deaths. Early research showed that patients with immunocompromise were at greater risk for developing more severe COVID-19 illness. This study investigated patients with HIV and their immunocompro-mised state (based on CD4 count and the presence of comorbidities) to better predict the severity of COVID-19. P = .66, df = 4. Chi -square analysis for the acute illness severity score compared with CD4 count resulted in a chi -square of 4.53, P = .33, df = 4. Both P values were greater than the desired P value of less than 0.05. The chi -square analysis suggested that no statistical signifi cance existed between the number of comorbidities and the severity of acute illness or CD4 count. Scatter plot regression was performed between the variables, and the R2 suggested no correlation between severity of acute illness and number of comorbidities or CD4 count closest to time of diagnosis of COVID-19.