Sex Determination and Ovarian Development in Reptiles and Amphibians: From Genetic Pathways to Environmental Influences.

IF 2.4 4区医学 Q2 DEVELOPMENTAL BIOLOGY

Sexual Development Pub Date : 2023-01-01 Epub Date: 2022-11-15 DOI:10.1159/000526009

Christopher R Smaga, Samantha L Bock, Josiah M Johnson, Benjamin B Parrott

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引用次数: 0

Abstract

Background: Reptiles and amphibians provide untapped potential for discovering how a diversity of genetic pathways and environmental conditions are incorporated into developmental processes that can lead to similar functional outcomes. These groups display a multitude of reproductive strategies, and whereas many attributes are conserved within groups and even across vertebrates, several aspects of sexual development show considerable variation.

Summary: In this review, we focus our attention on the development of the reptilian and amphibian ovary. First, we review and describe the events leading to ovarian development, including sex determination and ovarian maturation, through a comparative lens. We then describe how these events are influenced by environmental factors, focusing on temperature and exposure to anthropogenic chemicals. Lastly, we identify critical knowledge gaps and future research directions that will be crucial to moving forward in our understanding of ovarian development and the influences of the environment in reptiles and amphibians.

Key messages: Reptiles and amphibians provide excellent models for understanding the diversity of sex determination strategies and reproductive development. However, a greater understanding of the basic biology of these systems is necessary for deciphering the adaptive and potentially disruptive implications of embryo-by-environment interactions in a rapidly changing world.

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爬行动物和两栖动物的性别决定和卵巢发育:从遗传途径到环境影响。

背景:爬行动物和两栖动物提供了未开发的潜力，可以发现如何将多样性的遗传途径和环境条件纳入发育过程，从而导致类似的功能结果。这些群体表现出多种繁殖策略，尽管许多属性在群体内甚至在脊椎动物之间都是保守的，但性发育的几个方面表现出相当大的差异。摘要:本文对爬行动物和两栖动物卵巢的发育进行了综述。首先，我们回顾和描述导致卵巢发育的事件，包括性别决定和卵巢成熟，通过比较镜头。然后，我们描述了这些事件如何受到环境因素的影响，重点是温度和暴露于人为化学物质。最后，我们确定了关键的知识空白和未来的研究方向，这对我们理解爬行动物和两栖动物卵巢发育和环境影响至关重要。关键信息:爬行动物和两栖动物为理解性别决定策略的多样性和生殖发育提供了很好的模型。然而，在快速变化的世界中，对这些系统的基本生物学有更深入的了解是必要的，以便破译胚胎与环境相互作用的适应性和潜在破坏性含义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sexual Development 生物-发育生物学

CiteScore

4.00

自引率

4.30%

发文量

审稿时长

>12 weeks

期刊介绍： Recent discoveries in experimental and clinical research have led to impressive advances in our knowledge of the genetic and environmental mechanisms governing sex determination and differentiation, their evolution as well as the mutations or endocrine and metabolic abnormalities that interfere with normal gonadal development. ‘Sexual Development’ provides a unique forum for this rapidly expanding field. Its broad scope covers all aspects of genetics, molecular biology, embryology, endocrinology, evolution and pathology of sex determination and differentiation in humans and animals. It publishes high-quality original research manuscripts, review articles, short reports, case reports and commentaries. An internationally renowned and multidisciplinary editorial team of three chief editors, ten prominent scientists serving as section editors, and a distinguished panel of editorial board members ensures fast and author-friendly editorial processing and peer reviewing.