A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy.

Pub Date : 2022-11-11 eCollection Date: 2022-01-01 DOI:10.1055/a-1926-2053
Tom Malik, Robert Wheeler, Nigel J Hall, Juliet Gray
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Abstract

Mature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pregnancy but outcome data are limited. We present a case of prepubertal OTC in a 12-year-old girl undergoing a second oophorectomy for metachronous contralateral mature teratoma. We offer a discussion of the challenges that emerged regarding perioperative decision-making, balancing the need for safe oncological resection with the desire to preserve fertility.

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异时性双侧成熟卵巢畸胎瘤需双侧卵巢切除术一例青春期前卵巢组织冷冻保存。
成熟卵巢畸胎瘤有可能同时发生在对侧卵巢。双侧卵巢切除可能对生育有重要影响。在青春期前的女孩中,卵巢组织冷冻保存(OTC)提供了未来生物妊娠的唯一可能性,但结果数据有限。我们提出一个病例青春期前OTC在一个12岁的女孩接受第二次卵巢切除异时性对侧成熟畸胎瘤。我们提供了关于围手术期决策出现的挑战的讨论,平衡安全肿瘤切除的需要与保留生育能力的愿望。
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