A hierarchical logistic regression predicting rapid respiratory rates from post-exertional malaise.

IF 2.2 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Fatigue-Biomedicine Health and Behavior Pub Date : 2020-01-01 Epub Date: 2020-11-16 DOI:10.1080/21641846.2020.1845287

Joseph Cotler, Ben Z Katz, Corine Reurts-Post, Ruud Vermeulen, Leonard A Jason

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引用次数: 2

Abstract

Background: Past research has found high rates of hyperventilation in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), but hyperventilation can be influenced by psychological factors. Clinical respiratory rates have been less frequently assessed.

Aim: This study aimed to identify the predictors of rapid respiratory rates in patients referred to an outpatient clinic specializing in ME/CFS.

Methods: Adults (n = 216) referred to an outpatient clinic specializing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) participated in a two-day cardiopulmonary exercise test. As part of that evaluation, subjects had resting respiratory rates measured on two consecutive days. The current study used questionnaires to assess the relationship between tachypnea (rapid respiratory rates) and a variety of domains including post-exertional malaise (PEM), a common complaint in patients with ME/CFS, and psychiatric/somatic symptoms, using hierarchical logistic regression analysis.

Results: PEM was a significant predictor of tachypnea, while psychological/somatic assessments and sedentary behaviors were not significantly predictive of tachypnea.

Conclusions: These findings suggest that respiratory rate may be useful as an objective clinical metric of PEM, and potentially ME/CFS.

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分级逻辑回归预测运动后不适的快速呼吸速率。

背景:既往研究发现肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)患者换气过度发生率高，但换气过度可能受心理因素影响。临床呼吸频率评估较少。目的:本研究旨在确定在ME/CFS门诊就诊的患者快速呼吸率的预测因素。方法:在肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)门诊就诊的成年人(216例)参加了为期两天的心肺运动试验。作为评估的一部分，研究对象连续两天测量静息呼吸率。目前的研究采用问卷调查的方法评估呼吸急促(快速呼吸频率)与多种症状之间的关系，包括运动后不适(PEM)，这是ME/CFS患者的常见主诉，以及精神/躯体症状。结果:PEM是呼吸急促的显著预测因子，而心理/躯体评估和久坐行为对呼吸急促无显著预测作用。结论:这些发现提示呼吸频率可能是PEM的客观临床指标，也可能是ME/CFS的客观临床指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fatigue-Biomedicine Health and Behavior MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

5.20

自引率

7.10%

发文量

期刊介绍： Fatigue: Biomedicine, Health and Behavior is an international, interdisciplinary journal that addresses the symptom of fatigue in medical illnesses, behavioral disorders, and specific environmental conditions. These broadly conceived domains, all housed in one journal, are intended to advance research on causation, pathophysiology, assessment, and treatment. The list of topics covered in Fatigue will include fatigue in diseases including cancer, autoimmune diseases, multiple sclerosis, pain conditions, mood disorders, and circulatory diseases. The journal will also publish papers on chronic fatigue syndrome, fibromyalgia and related illnesses. In addition, submissions on specific issues involving fatigue in sleep, aging, exercise and sport, and occupations are welcomed. More generally, the journal will publish on the biology, physiology and psychosocial aspects of fatigue. The Editor also welcomes new topics such as clinical fatigue education in medical schools and public health policy with respect to fatigue.