Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022.

Jacob Kofler, Alban Ramette, Patricia Iseli, Lea Stauber, Jens Fichtner, Sara Droz, Annina Zihler Berner, Anna Bettina Meier, Michelle Begert, Sabine Negri, Anne Jachmann, Peter Michael Keller, Cornelia Staehelin, Barbara Grützmacher
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引用次数: 12

Abstract

Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin. Phylogenomic analyses showed evidence of imported and local transmissions of toxigenic strains in respiratory and skin lesion samples. Given the number of cases (n = 20) and the large genetic diversity accumulating in one centre, increased awareness and changes in public health measures are required to prevent and control diphtheria outbreaks.

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瑞士联邦庇护中心正在爆发毒素阳性白喉疫情,分析于2022年7月至9月。
2022年7月至10月在瑞士庇护中心发生了两次白喉疫情,其中一次仍在进行中。暴发主要涉及未成年人,包括6例需要抗毒素的有症状的呼吸性白喉病例。系统基因组学分析显示,在呼吸道和皮肤病变样本中存在输入性和本地产毒菌株传播的证据。鉴于病例数(n = 20)和在一个中心积累的大量遗传多样性,需要提高认识并改变公共卫生措施,以预防和控制白喉的爆发。
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