Functional improvement in children and adolescents with primary headache after an interdisciplinary multimodal therapy program: the DreKiP study.

Hanna Sobe, Matthias Richter, Reinhard Berner, Maja von der Hagen, Antje Hähner, Ingo Röder, Thea Koch, Rainer Sabatowski, Anna Klimova, Gudrun Gossrau
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引用次数: 3

Abstract

Background: More than 2/3 of children and adolescents in Germany regularly suffer from headaches. Headache-related limitations in everyday life, school drop-out and educational impairment are common. Structured therapy programs for young headache patients are widely missing.

Methods: One hundred eleven patients with frequent migraine and/or tension type headache were treated in a 15 hour group program in afternoons, parallel with school, parents received 7 hours of therapy. At the beginning of the program (T0), 6 (T1) and 12 months (T2) after completion, data on headache related disability (PedMidas), headache frequency, intensity, and pediatric pain disability score (PPDI) were prospectively collected to investigate the effects of the therapy.

Results: Seventy-five patients (9-19 years, median = 14; 66.7% female) and their parents provided patient reported outcome measures showing at T1 (65 patients) and T2 (47 patients) reduced headache frequency (last 3 months headache days median T0: 30 days; T1: 18 days, reduction of median 12 days since T0; T2: 13 days, reduction of median 17 days since T0). Linear mixed models revealed significant reduction (T0/T1 p = 0,002; T0/T2 p = 0,001). Reduced headache disability has been reported at T1 and T2 (PedMidas median T0 = 30, T1 = 15, T2 = 7; p < 0,001, p < 0,001 respectively). Follow up data of a subgroup of patients 24 months after the treatment point to sustainable effects.

Conclusions: The interdisciplinary multimodal headache therapy program DreKiP reduces headache frequency and headache related disability significantly 6-12 months following its completion.

Trial registration: DRKS00027523, retrospectively registered.

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跨学科多模式治疗方案后儿童和青少年原发性头痛的功能改善:DreKiP研究
背景:德国超过2/3的儿童和青少年经常患有头痛。日常生活中与头痛相关的限制、辍学和教育障碍是常见的。针对年轻头痛患者的结构化治疗方案普遍缺失。方法:111例频繁偏头痛和/或紧张性头痛患者在下午接受15小时的小组治疗,与学校平行,家长接受7小时的治疗。在项目开始(T0), 6 (T1)和完成后12个月(T2),前瞻性收集头痛相关残疾(PedMidas),头痛频率,强度和儿科疼痛残疾评分(PPDI)的数据,以研究治疗的效果。结果:75例患者(9-19岁,中位= 14;66.7%女性)及其父母提供了患者报告的结果测量结果,显示T1(65例患者)和T2(47例患者)头痛频率减少(最近3个月头痛天数中位数为30天;T1: 18天,自T0起中位减少12天;T2: 13天,自T0以来平均减少17天)。线性混合模型显示显著降低(T0/T1 p = 0,002;T0/T2 p = 0.001)。在T1和T2时有报道头痛功能障碍减少(PedMidas中位T0 = 30, T1 = 15, T2 = 7;结论:跨学科多模式头痛治疗项目DreKiP在完成后6-12个月显著降低头痛频率和头痛相关残疾。试验注册:DRKS00027523,回顾性注册。
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