EVALUATION OF THE FUNCTIONAL STATE OF LIVER AND THE EFFICIENCY OF THERAPY FOR ENTEROPATHY OF CALVES.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Pub Date : 2016-01-01 DOI:10.15407/fz62.06.102

V A Gryshchenko, T M Chernyshenko, O V Gornitska, T M Platonova

{"title":"EVALUATION OF THE FUNCTIONAL STATE OF LIVER AND THE EFFICIENCY OF THERAPY FOR ENTEROPATHY OF CALVES.","authors":"V A Gryshchenko, T M Chernyshenko, O V Gornitska, T M Platonova","doi":"10.15407/fz62.06.102","DOIUrl":null,"url":null,"abstract":"<p><p>Comprehensive study of hepatospecific biochemical blood markers and haemostatic system in calves which recovered from gastrointestinal pathology at age 2-7 days, was con- ducted. Implementation of a complex of tests for evaluation of the liver's functional state and the efficiency of therapeutic regimens shown that the experimental animals compared to control at the 30th day of life demonstrated significantly increased conjugated bilirubin concentration (1.6 times), aspartate- and alanin aminotransferase activity (1.2 times), gamma-glutamyl transpeptidase (1.5 times) and alkaline phosphatase (1.4 times), and content of soluble fibrin monomer complexes (4 times). Such deviation from the norm of the mentioned parameters of liver's functional state suggests the need to monitor the liver state even 3 weeks after their clinical health is confirmed. To prevent the development of secondary hepatopathology it is recommended to conduct further medical correction of the functional state of the liver. It is found that to stimulate recovery of liver function in case of toxic dyspepsia in newborn calves, it is advisable to implement a phospholipid containing supplement <FLP-MDn as a measure ofreparative therapy till the animals are 30 days of life to ensure successful establishing of studied parameters.</p>","PeriodicalId":73031,"journal":{"name":"Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)","volume":"62 6","pages":"102-109"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15407/fz62.06.102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 7

Abstract

Comprehensive study of hepatospecific biochemical blood markers and haemostatic system in calves which recovered from gastrointestinal pathology at age 2-7 days, was con- ducted. Implementation of a complex of tests for evaluation of the liver's functional state and the efficiency of therapeutic regimens shown that the experimental animals compared to control at the 30th day of life demonstrated significantly increased conjugated bilirubin concentration (1.6 times), aspartate- and alanin aminotransferase activity (1.2 times), gamma-glutamyl transpeptidase (1.5 times) and alkaline phosphatase (1.4 times), and content of soluble fibrin monomer complexes (4 times). Such deviation from the norm of the mentioned parameters of liver's functional state suggests the need to monitor the liver state even 3 weeks after their clinical health is confirmed. To prevent the development of secondary hepatopathology it is recommended to conduct further medical correction of the functional state of the liver. It is found that to stimulate recovery of liver function in case of toxic dyspepsia in newborn calves, it is advisable to implement a phospholipid containing supplement

查看原文本刊更多论文

犊牛肠病肝脏功能状态及治疗效果评价。

对2 ~ 7日龄胃肠病恢复犊牛肝脏特异性生化血液标志物和止血系统进行了全面研究。对肝脏功能状态评估和治疗方案效率的一系列测试表明，与对照组相比，实验动物在30天的生命中显示出显著增加的结合胆红素浓度(1.6倍)，天冬氨酸和丙氨酸转氨酶活性(1.2倍)，γ -谷氨酰转肽酶(1.5倍)和碱性磷酸酶(1.4倍)，可溶性纤维蛋白单体复合物的含量(4倍)。上述肝脏功能状态参数与标准的偏差表明，即使在临床确认健康后3周，也需要监测肝脏状态。为了防止继发性肝病理的发展，建议对肝脏的功能状态进行进一步的医学校正。研究发现，在中毒性消化不良的情况下，为了促进新生牛犊肝功能的恢复，建议使用含磷脂的补充剂

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)

CiteScore

0.60

自引率

0.00%

发文量