Percutaneous balloon pericardiotomy: efficacy in a series of malignant and nonmalignant cases.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Holger H Sigusch, Wolff Geisler, Ralf Surber, Marc Schönweiß, Jens Gerth
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引用次数: 1

Abstract

Objective: In the case of malignant pericardial effusion and cardiac tamponade, balloon pericardiotomy is an established minimally invasive option to the surgical creation of a subxiphoid pericardial window. Percutaneous balloon pericardiotomy effectively drains recurrent pericardial fluid by creating a pleuro (-abdominal-) pericardial communication. Design. A series of 26 patients with underlying malignant (n = 12) and nonmalignant (n = 14) diseases underwent percutaneous balloon pericardiotomy between 2008 and 2021. All interventions were done through a subxiphoid access under local anesthesia. Results. The mean survival in the malignant and nonmalignant groups was 1.2 versus 48.0 months, respectively (p < .001). There were neither severe periinterventional complications nor in-hospital deaths. In two patients with nonmalignant disease the surgical creation of a pericardial window was necessary during follow-up. The originally described procedure was modified by the removal of all catheters at the end of the intervention. The procedure was safe. It prevented immobility and facilitated an early discharge from the hospital. Conclusion. Our experiences show that percutaneous balloon pericardiotomy is a minimally invasive approach to successfully provide palliation in the group of patients with underlying malignant disease. On the other hand, we have shown that this technique is safe and feasible in the treatment of pericardial effusion based on nonmalignant disease. We think thereby that pericardial balloon pericardiotomy can be considered as a less invasive alternative to surgery in both groups of patients.

经皮球囊心包切开术:一系列恶性和非恶性病例的疗效。
目的:在恶性心包积液和心包填塞的情况下,球囊心包切开术是一种建立剑突下心包窗的微创选择。经皮球囊心包切开术通过建立胸膜(腹膜-心包)通心包,有效排出反复出现的心包积液。设计。2008年至2021年间,26例潜在恶性(n = 12)和非恶性(n = 14)疾病患者接受了经皮球囊心包切开术。所有干预均在局部麻醉下通过剑突下通路进行。结果。恶性组和非恶性组的平均生存期分别为1.2个月和48.0个月(p。我们的经验表明,经皮球囊心包切开术是一种微创的方法,可以成功地为有潜在恶性疾病的患者提供缓解。另一方面,我们已经证明这种技术在治疗基于非恶性疾病的心包积液方面是安全可行的。因此,我们认为在两组患者中,心包球囊心包切开术可被认为是一种侵入性较小的手术选择。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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