Evaluation of the potential pathogenicity of microorganisms associated with urinary calculi.

Q4 Health Professions

Klinichescheskaya Laboratornaya Diagnostika Pub Date : 2022-06-20 DOI:10.51620/0869-2084-2022-67-6-369-373

N I Ignatova, V V Elagin, T S Ivanova, T M Kharitonova, A E Antonyan, O S Streltsova

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引用次数: 1

Abstract

Due to the prevalence of postoperative complications in the treatment of urolithiasis, the study of the contamination of urinary calculi and the potential pathogenicity of isolated bacteria is of great importance in laboratory diagnostic practice. It has been shown that uropathogenic bacteria are found in the composition of urinary stones in 65±7.1% of cases, mainly representatives of the Enterobacteriaceae and Staphylococcaceae families. Bacteria of the generas Escherichia, Enterococcus, Staphylococcus were most frequently detected. The analysis of biofilm activity and antibiotic resistance in 50 uropathogenic strains was carried out. It was shown that all the studied strains were resistant to at least two tested drugs, and the average value of the multiple resistance index was 0.51. When cultured on nutrient agar with Congo red, it was shown that more than half of the tested strains have high biofilm activity and about 80% potential for biofilm formation. The greatest biofilm activity was observed in bacteria of the generas Escherichia, Klebsiella, Enterobacter, Staphylococcus.

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与尿路结石相关的微生物潜在致病性的评估。

由于尿石症术后并发症的普遍存在，研究尿石的污染和分离细菌的潜在致病性在实验室诊断实践中具有重要意义。研究表明，尿路结石组成中检出尿路致病菌的比例为65±7.1%，主要为肠杆菌科和葡萄球菌科的代表菌。以大肠杆菌属、肠球菌属、葡萄球菌属细菌检出最多。对50株尿路病原菌的生物膜活性和耐药性进行了分析。结果表明，所有研究菌株均对至少两种被试药物耐药，多重耐药指数平均值为0.51。在刚果红营养琼脂上培养时，半数以上的菌株具有较高的生物膜活性，形成生物膜的可能性约为80%。大肠杆菌属、克雷伯氏菌属、肠杆菌属、葡萄球菌属的生物膜活性最高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Klinichescheskaya Laboratornaya Diagnostika Health Professions-Medical Laboratory Technology

CiteScore

0.90

自引率

0.00%

发文量

110

期刊介绍： The journal deals with theoretical and practical problems of clinical laboratory diagnosis, publishes editorial articles, reviews of literature, original articles, short reports, discussions, book reviews, current events, materials which may assist the practitioners, methods of laboratory investigations used in medicine, materials on the results of practical application of new methods of investigation in the following fields of clinical laboratory diagnosis: hematology, cytology, coagulation, biochemistry, immunology.