Left ventricle accessory antero-septal papillary muscle: an echocardiography and cardiac MRI case-series report.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2022-11-23 Print Date: 2022-12-01 DOI:10.2478/rjim-2022-0017
George O Angheloiu, Robert W Biederman
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引用次数: 0

Abstract

Background. We studied by means of echocardiography and cardiac MRI (CMR) the occurrence of an accessory papillary muscle that unites mostly the left ventricle (LV) apex with the basal antero-septum in the immediate vicinity of left ventricle outflow tract (LVOT) in patients with and without hypertrophic cardiomyopathy (HOCM). Methods. We included all good quality echocardiography and CMR studies as reviewed by two cardiologists and assessed the occurrence of a contractile papillary muscle situated between the LV apex and antero-septum. Results. A contractile accessory papillary muscle situated between the LV apex and the anteroseptum was seen in 100% of HOCM patients and 62% of control patients (p=0.05) in the CMR images acquired from a total of 9 HOCM and 13 control patients. The same structure was observed in 241 patients representing 69.5% of all-comers echocardiography studies. The age was 69 ± 17 years on average in the echocardiography arm, patients harboring the antero-septal accessory muscle being older (71.6 + 15.7 years old vs 63.5 ± 18.1 for those without, p=0.0005). We exemplify this structure by parasternal long axis still echocardiography images and clips from 24 patients and CMR SSFP still images and a clip from two HOCM patients and one control. Conclusion. A contractile accessory papillary muscle was observed in more than half of the all-comer echocardiography studies, and in all HOCM patients in the CMR arm. Further research is needed to fully characterize the anatomical and physiological significance as well as the possible structural interventional consequences of this structure attaching in the immediate vicinity of the LVOT in HOCM and control patients.

左心室副前间隔乳头状肌:超声心动图和心脏MRI病例系列报告。
背景。我们通过超声心动图和心脏MRI (CMR)研究了肥厚性心肌病(HOCM)患者在左心室流出道(LVOT)附近大部分连接左心室(LV)顶点和基底前隔的副乳头肌的发生。方法。我们纳入了所有高质量的超声心动图和CMR研究,并评估了位于左室心尖和前隔膜之间的收缩乳头肌的发生。结果。在9例HOCM患者和13例对照组患者的CMR图像中,100%的HOCM患者和62%的对照组患者可见位于左室尖部和前间隔之间的可收缩的副乳头肌(p=0.05)。在241例患者中观察到相同的结构,占所有患者超声心动图研究的69.5%。超声心动图组平均年龄为69±17岁,有前间隔副肌组平均年龄为71.6±15.7岁,无前间隔副肌组平均年龄为63.5±18.1岁,p=0.0005。我们通过来自24名患者的胸骨旁长轴静止超声心动图图像和片段以及来自两名HOCM患者和一名对照者的CMR SSFP静止图像和片段来举例说明这种结构。结论。超过一半的超声心动图研究和CMR组的所有HOCM患者均观察到副乳头肌收缩。在HOCM和对照组患者中,该结构附着在LVOT附近的解剖和生理意义,以及可能的结构介入后果,需要进一步的研究来充分表征。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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