CLINICAL IMPLICATION OF RETINAL NERVE FIBER LAYER SCHISIS AND MACULAR FLUORESCEIN LEAKAGE IN PRIMARY IDIOPATHIC EPIRETINAL MEMBRANE.

Retina (Philadelphia, Pa.) Pub Date : 2022-12-01 DOI:10.1097/IAE.0000000000003623

Jonghyun Kim, Seong-Woo Kim, Mihyun Choi, Cheolmin Yun, Jaeryung Oh

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Abstract

Purpose: We evaluated the relationship between macular fluorescein leakage and retinal nerve fiber layer (RNFL) schisis and investigated the visual prognostic values after pars plana vitrectomy (PPV) and idiopathic epiretinal membrane removal.

Methods: We analyzed the correlations between preoperative optical coherence tomography (OCT) parameters and macular leakage. The final best-corrected visual acuity and central macular thickness were compared according to the presence or absence of macular leakage and RNFL schisis.

Results: In 80 eyes with idiopathic epiretinal membrane treated with PPV and membrane peeling, preoperative macular leakage was associated with the presence of preoperative RNFL schisis and inner nuclear layer microcysts. Eyes with both macular leakage and RNFL schisis showed worse postoperative best-corrected visual acuity than those without both factors.

Conclusion: In the presence of macular fluorescein leakage and RNFL schisis, postoperative best-corrected visual acuity is worse, and improvements in the central macular thickness are greater than those in the absence of both factors.

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原发性特发性视网膜前膜视网膜神经纤维层断裂及黄斑荧光素渗漏的临床意义。

目的:评价黄斑荧光素渗漏与视网膜神经纤维层(RNFL)断裂的关系，探讨睫状体平面肌玻璃体切除术(PPV)和特发性视网膜前膜切除术后的视觉预后价值。方法:分析术前光学相干断层扫描(OCT)参数与黄斑渗漏的相关性。根据是否存在黄斑渗漏和RNFL裂，比较最终最佳矫正视力和中央黄斑厚度。结果:80只特发性视网膜前膜经PPV和膜剥离治疗的眼，术前黄斑渗漏与术前RNFL裂裂和内核层微囊的存在有关。同时存在黄斑渗漏和RNFL裂的眼的术后最佳矫正视力较不存在这两种因素的眼差。结论:存在黄斑荧光素渗漏和RNFL分裂时，术后最佳矫正视力较差，黄斑中央厚度的改善大于无这两种因素时。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Retina (Philadelphia, Pa.)

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