{"title":"[Thyroid and SARS-CoV-2].","authors":"Georg Zettinig","doi":"10.1007/s41969-022-00173-0","DOIUrl":null,"url":null,"abstract":"<p><p>There are several interactions between a SARS-CoV‑2 infection and the thyroid, bidirectionally in both directions. In severe COVID-19 infection, changes in thyroid hormone levels are a marker for poorer prognosis. SARS-CoV‑2 appears to interact directly with thyrocytes as well as modulate the immune system and trigger autoimmune thyroid disease. As early as 2020, SARS-CoV‑2 associated thyroiditis was described in patients with COVID-19, which is similar to subacute thyroiditis but typically painless. There are now a wide variety of reports on the occurrence of chronic autoimmune thyroiditis and Graves' disease following both viral infection and vaccination. Existing thyroid disease does not appear to be associated with either a higher risk of SARS-CoV‑2 infection or a more severe disease course. The present paper summarizes the current knowledge regarding the thyroid gland and SARS-CoV‑2.</p>","PeriodicalId":40772,"journal":{"name":"Austrian Journal of Clinical Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":0.1000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437391/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Austrian Journal of Clinical Endocrinology and Metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s41969-022-00173-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/9/2 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
There are several interactions between a SARS-CoV‑2 infection and the thyroid, bidirectionally in both directions. In severe COVID-19 infection, changes in thyroid hormone levels are a marker for poorer prognosis. SARS-CoV‑2 appears to interact directly with thyrocytes as well as modulate the immune system and trigger autoimmune thyroid disease. As early as 2020, SARS-CoV‑2 associated thyroiditis was described in patients with COVID-19, which is similar to subacute thyroiditis but typically painless. There are now a wide variety of reports on the occurrence of chronic autoimmune thyroiditis and Graves' disease following both viral infection and vaccination. Existing thyroid disease does not appear to be associated with either a higher risk of SARS-CoV‑2 infection or a more severe disease course. The present paper summarizes the current knowledge regarding the thyroid gland and SARS-CoV‑2.
期刊介绍:
Das Journal für Klinische Endokrinologie und Stoffwechsel veröffentlicht Originalarbeiten, Übersichten, Fallberichte, Kurzberichte sowie Kommentare aus allen Bereichen der Endokrinologie und Stoffwechselerkrankungen. Experimentelle Untersuchungen sollen einen direkten klinischen Bezug aufweisen. Das Journal versteht sich als praxisorientiertes Fortbildungsmagazin und möchte Aktualität und Wissen vermitteln. Namhafte Expert*innen kommen zu Wort und beleuchten Schwerpunkte des Praxisalltags. Dadurch soll die Einbindung neuester Erkenntnisse in die tägliche Routinearbeit erleichtert werden.