A Secondary Analysis from The International BRIGHT Study For Gender Differences In Adherence To Nonpharmacological Health-Related Behaviors After Heart Transplantation.

Abstract

Heart transplant is an established treatment for selected patients with end-stage heart failure. Maximizing long-term survival is a primary focus of posttransplant management and research. Optimal outcomes after transplantation require adherence to a complex therapeutic regimen consisting of immunosuppressants, co-medications and nonpharmacological health-related behaviors, such as sun protection, sufficient physical activity, appropriate diet, smoking cessation, appropriate alcohol use and appointment adherence to follow-up visits. Adherence to nonpharmacological treatment can reduce the risk after transplant just as in the general population. Chronic exposure to immunosuppressant medications has potential serious side effects within 10 years of transplantation, including hypertension (70-90%), dyslipidemia (>50%), diabetes