Age Predicts Functional Outcome in Acute Stroke Patients with rt-PA Treatment.

ISRN Neurology Pub Date : 2013-09-19 eCollection Date: 2013-01-01 DOI:10.1155/2013/710681

Jarin Chindaprasirt, Kittisak Sawanyawisuth, Paiboon Chattakul, Panita Limpawattana, Somsak Tiamkao, Patcharin Aountri, Verajit Chotmongkol

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引用次数: 14

Abstract

The standard treatment for acute ischemic stroke is thrombolytic therapy. There is limited data on prognostic factors of acute stroke with thrombolytic therapy particularly in Asian population. Acute ischemic stroke patients who were treated with thrombolytic therapy at Srinagarind Hospital between May 2008 and July 2010 were included. Factors associated with Barthel index more than 80 were studied by multiple logistic regression analysis. There were 75 patients included in the study. The mean NIHSS scores before treatment and at 3 months were 9.16 ± 4.82 and 3.83 ± 4.00, respectively, and median Barthel index at 3 months was 86. Only significant predictor for having Barthel index more than 80 points at 3 months was age (adjusted odds ratio 0.929, 95% confidence interval 0.874, 0.988). Four patients developed intracranial hemorrhage after the treatment (5%), and two died (2.6%). In conclusion, age predicts Barthel index in acute stroke patients with rt-PA treatment.

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年龄预测急性脑卒中患者rt-PA治疗的功能结局。

急性缺血性中风的标准治疗是溶栓治疗。关于急性脑卒中溶栓治疗预后因素的数据有限，特别是在亚洲人群中。纳入2008年5月至2010年7月期间在斯利那加林医院接受溶栓治疗的急性缺血性中风患者。对Barthel指数大于80的相关因素进行多元logistic回归分析。这项研究包括75名患者。治疗前和治疗3个月时NIHSS平均评分分别为9.16±4.82和3.83±4.00，治疗3个月时Barthel指数中位数为86。3个月时Barthel指数大于80点的唯一显著预测因子是年龄(校正优势比0.929,95%可信区间0.874,0.988)。治疗后发生颅内出血4例(5%)，死亡2例(2.6%)。结论:年龄对急性脑卒中rt-PA治疗患者Barthel指数有预测作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ISRN Neurology

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